Relaxant Effects of Matrine on Aortic Smooth Muscles of Guinea Pigs

Objective To determine whether matrine, a kind of traditional Chinese medicinal alkaloid, can relax the aortic smooth muscles isolated from guinea pigs and to investigate the mechanism of its relaxant effects. Methods Phenylephrine or potassium chloride concentration-dependent relaxation response of...

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Veröffentlicht in:	Biomedical and environmental sciences 2009-08, Vol.22 (4), p.327-332, Article 327
Hauptverfasser:	ZHENG, JIE, ZHENG, PING, ZHOU, XU, YAN, LIN, ZHOU, RU, FU, XUE-YAN, DAI, GUI-DONG
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaloids - chemistry Alkaloids - pharmacology Animals Aorta Aorta - drug effects Aorta - physiology Calcium Calcium - pharmacology Culture Media - pharmacology Dose-Response Relationship, Drug Glyburide - pharmacology Guinea Pigs In Vitro Techniques Male Matrine Muscle Contraction - drug effects Muscle Relaxation - drug effects Muscle, Smooth, Vascular - drug effects Muscle, Smooth, Vascular - physiology Phenylephrine - pharmacology Potassium Chloride - pharmacology Propranolol - pharmacology Quinolizines - chemistry Quinolizines - pharmacology Relaxation Tetraethylammonium - pharmacology Vascular smooth muscle 大动脉肌肉生物医学苦参碱钙离子
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