ZrOCl2·SiO2-catalyzed synthesis of bis(indoles) via conjugate addition of indole with electron-deficient alkenes in water

ZrOCl2·SiO2-catalyzed synthesis of bis(indoles) via conjugate addition of indole with electron-deficient alkenes in water

This report provides a description of an efficient and environmentally benign procedure for the synthesis of bis(indole) derivatives via reaction of indole with electron-deficient alkenes. The remarkable advantages of this method for obtaining bis(indoles) are the simplicity of the experimental proc...

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Veröffentlicht in:Heterocyclic communications 2015-04, Vol.21 (2), p.89-92
Hauptverfasser: Jari, Tayebeh, Amrollahi, Mohammad Ali, Kheilkordi, Zohreh
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Sprache:eng
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aqueous media
bis(indole)
Michael addition
oxidative dehydrogenation
zirconium oxychloride
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container_end_page 92
container_issue 2
container_start_page 89
container_title Heterocyclic communications
container_volume 21
creator Jari, Tayebeh
Amrollahi, Mohammad Ali
Kheilkordi, Zohreh
description This report provides a description of an efficient and environmentally benign procedure for the synthesis of bis(indole) derivatives via reaction of indole with electron-deficient alkenes. The remarkable advantages of this method for obtaining bis(indoles) are the simplicity of the experimental procedure, short reaction times, and high yields with the green aspects by avoiding toxic catalysts and solvents.
doi_str_mv 10.1515/hc-2015-0014
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source De Gruyter Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects aqueous media
bis(indole)
Michael addition
oxidative dehydrogenation
zirconium oxychloride
title ZrOCl2·SiO2-catalyzed synthesis of bis(indoles) via conjugate addition of indole with electron-deficient alkenes in water
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