Amide compounds as boosters of antivirals

Amide compounds as boosters of antivirals

The present invention relates to compounds that have CYP450 inhibiting properties and are therefore useful as boosters of certain drugs, i.e. they are able to increase at least one of the pharmacokinetic variables of certain drugs when co-administered. The invention further provides the use of said...

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Hauptverfasser: Jonckers, Tim Hugo Maria, Schepens, Wim Bert Griet, Haché, Geerwin Yvonne Paul, Hallenberger, Beate Sabine, Sasaki, Jennifer Chiyomi, Baumeister, Judith Eva, Van 'T Klooster, Gerben Albert
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creator Jonckers, Tim Hugo Maria
Schepens, Wim Bert Griet
Haché, Geerwin Yvonne Paul
Hallenberger, Beate Sabine
Sasaki, Jennifer Chiyomi
Baumeister, Judith Eva
Van 'T Klooster, Gerben Albert
description The present invention relates to compounds that have CYP450 inhibiting properties and are therefore useful as boosters of certain drugs, i.e. they are able to increase at least one of the pharmacokinetic variables of certain drugs when co-administered. The invention further provides the use of said compounds as improvers of the bioavailability of certain drugs. Methods for the preparation of the compounds of the invention and pharmaceutical compositions are also provided.
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title Amide compounds as boosters of antivirals
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