Methods for inducing differentiation of undifferentiated mammalian cells into osteoblasts

The present invention relates to in vivo and in vitro methods, agents and compound screening assays for inducing differentiation of undifferentiated mammalian cells into osteoblasts, including bone formation enhancing pharmaceutical compositions, and the use thereof in treating and/or preventing a d...

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Bibliographische Detailangaben
Hauptverfasser: Van Rompaey, Luc Juliaan Corina, Tomme, Peter Herwig Maria, Brown, Robin John
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to in vivo and in vitro methods, agents and compound screening assays for inducing differentiation of undifferentiated mammalian cells into osteoblasts, including bone formation enhancing pharmaceutical compositions, and the use thereof in treating and/or preventing a disease involving a systemic or local decrease in mean bone density in a subject.