CD37 immunotherapeutics and uses thereof

CD37 immunotherapeutics and uses thereof

The present disclosure provides a humanized anti-CD37 small modular immunopharmaceutical (SMIP) molecule, as well as synergistic combination therapies of CD37-specific binding molecules (such as anti-CD37 SMIP proteins or antibodies) with bifunctional chemotherapeutics (such as bendamustine) that ca...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tan, Philip, Simon, Sandy Alexander, Brady, William, Morales, Cecile
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present disclosure provides a humanized anti-CD37 small modular immunopharmaceutical (SMIP) molecule, as well as synergistic combination therapies of CD37-specific binding molecules (such as anti-CD37 SMIP proteins or antibodies) with bifunctional chemotherapeutics (such as bendamustine) that can be administered concurrently or sequentially, for use in treating or preventing B cell related autoimmune, inflammatory, or hyperproliferative diseases.