Metalloprotein inhibitors
1234 The present invention relates to metalloprotein inhibitors comprising: a. an organic substituent and at least one zinc binding group (ZBG) covalently attached thereto; or b. a ZBG substituted by a side chain wherein the ZBG is of formula (I): wherein X is O or S and each R, R, R, and Ris indivi...
Gespeichert in:
Hauptverfasser: | , , |
---|---|
Format: | Patent |
Sprache: | eng |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | |
---|---|
container_issue | |
container_start_page | |
container_title | |
container_volume | |
creator | Puerta, David T Cohen, Seth M Lewis, Jana A |
description | 1234 The present invention relates to metalloprotein inhibitors comprising: a. an organic substituent and at least one zinc binding group (ZBG) covalently attached thereto; or b. a ZBG substituted by a side chain wherein the ZBG is of formula (I): wherein X is O or S and each R, R, R, and Ris individually hydrogen or an organic radical. The metalloprotein inhibitors are useful for preventing or treating a pathological disease, condition, or symptom that is associated with pathological metalloprotein activity and/or that is alleviated by inhibition of said activity. |
format | Patent |
fullrecord | <record><control><sourceid>uspatents_EFH</sourceid><recordid>TN_cdi_uspatents_grants_08318945</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>08318945</sourcerecordid><originalsourceid>FETCH-uspatents_grants_083189453</originalsourceid><addsrcrecordid>eNrjZJD0TS1JzMnJLyjKL0nNzFPIzMvITMosyS8q5mFgTUvMKU7lhdLcDApuriHOHrqlxQWJJal5JcXx6UWJIMrAwtjQwtLE1JgIJQA9ICQk</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Metalloprotein inhibitors</title><source>USPTO Issued Patents</source><creator>Puerta, David T ; Cohen, Seth M ; Lewis, Jana A</creator><creatorcontrib>Puerta, David T ; Cohen, Seth M ; Lewis, Jana A ; The Regents of the University of California</creatorcontrib><description>1234 The present invention relates to metalloprotein inhibitors comprising: a. an organic substituent and at least one zinc binding group (ZBG) covalently attached thereto; or b. a ZBG substituted by a side chain wherein the ZBG is of formula (I): wherein X is O or S and each R, R, R, and Ris individually hydrogen or an organic radical. The metalloprotein inhibitors are useful for preventing or treating a pathological disease, condition, or symptom that is associated with pathological metalloprotein activity and/or that is alleviated by inhibition of said activity.</description><language>eng</language><creationdate>2012</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8318945$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,776,798,881,64015</link.rule.ids><linktorsrc>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8318945$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Puerta, David T</creatorcontrib><creatorcontrib>Cohen, Seth M</creatorcontrib><creatorcontrib>Lewis, Jana A</creatorcontrib><creatorcontrib>The Regents of the University of California</creatorcontrib><title>Metalloprotein inhibitors</title><description>1234 The present invention relates to metalloprotein inhibitors comprising: a. an organic substituent and at least one zinc binding group (ZBG) covalently attached thereto; or b. a ZBG substituted by a side chain wherein the ZBG is of formula (I): wherein X is O or S and each R, R, R, and Ris individually hydrogen or an organic radical. The metalloprotein inhibitors are useful for preventing or treating a pathological disease, condition, or symptom that is associated with pathological metalloprotein activity and/or that is alleviated by inhibition of said activity.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2012</creationdate><recordtype>patent</recordtype><sourceid>EFH</sourceid><recordid>eNrjZJD0TS1JzMnJLyjKL0nNzFPIzMvITMosyS8q5mFgTUvMKU7lhdLcDApuriHOHrqlxQWJJal5JcXx6UWJIMrAwtjQwtLE1JgIJQA9ICQk</recordid><startdate>20121127</startdate><enddate>20121127</enddate><creator>Puerta, David T</creator><creator>Cohen, Seth M</creator><creator>Lewis, Jana A</creator><scope>EFH</scope></search><sort><creationdate>20121127</creationdate><title>Metalloprotein inhibitors</title><author>Puerta, David T ; Cohen, Seth M ; Lewis, Jana A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_grants_083189453</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2012</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Puerta, David T</creatorcontrib><creatorcontrib>Cohen, Seth M</creatorcontrib><creatorcontrib>Lewis, Jana A</creatorcontrib><creatorcontrib>The Regents of the University of California</creatorcontrib><collection>USPTO Issued Patents</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Puerta, David T</au><au>Cohen, Seth M</au><au>Lewis, Jana A</au><aucorp>The Regents of the University of California</aucorp><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Metalloprotein inhibitors</title><date>2012-11-27</date><risdate>2012</risdate><abstract>1234 The present invention relates to metalloprotein inhibitors comprising: a. an organic substituent and at least one zinc binding group (ZBG) covalently attached thereto; or b. a ZBG substituted by a side chain wherein the ZBG is of formula (I): wherein X is O or S and each R, R, R, and Ris individually hydrogen or an organic radical. The metalloprotein inhibitors are useful for preventing or treating a pathological disease, condition, or symptom that is associated with pathological metalloprotein activity and/or that is alleviated by inhibition of said activity.</abstract><oa>free_for_read</oa></addata></record> |
fulltext | fulltext_linktorsrc |
identifier | |
ispartof | |
issn | |
language | eng |
recordid | cdi_uspatents_grants_08318945 |
source | USPTO Issued Patents |
title | Metalloprotein inhibitors |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-26T20%3A10%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-uspatents_EFH&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Puerta,%20David%20T&rft.aucorp=The%20Regents%20of%20the%20University%20of%20California&rft.date=2012-11-27&rft_id=info:doi/&rft_dat=%3Cuspatents_EFH%3E08318945%3C/uspatents_EFH%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |