Pyridone derivatives as p38α MAPK inhibitors

Pyridone derivatives as p38α MAPK inhibitors

1 2 3 4 5 6 A compound represented by the formula (I): wherein Ris lower alkyl, cycloalkyl or aromatic hydrocarbon ring, each of which is optionally substituted with one or more substituents; Ris hydrogen atom, halogen atom, lower alkyl, halo(lower)alkyl or lower alkoxy; and Ris (1) a group represen...

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Hauptverfasser: Kasahara, Chiyoshi, Yamazaki, Hitoshi
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creator Kasahara, Chiyoshi
Yamazaki, Hitoshi
description 1 2 3 4 5 6 A compound represented by the formula (I): wherein Ris lower alkyl, cycloalkyl or aromatic hydrocarbon ring, each of which is optionally substituted with one or more substituents; Ris hydrogen atom, halogen atom, lower alkyl, halo(lower)alkyl or lower alkoxy; and Ris (1) a group represented by the formula: wherein Ris lower alkyl, etc.; (2) a group represented by the formula: wherein Ris lower alkyl, etc.; (3) a group represented by the formula: wherein Ris lower alkyl, etc.; or (4) a group selected from halogen atom, carboxy, hydroxy and lower alkoxy, or a salt thereof.
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Ris hydrogen atom, halogen atom, lower alkyl, halo(lower)alkyl or lower alkoxy; and Ris (1) a group represented by the formula: wherein Ris lower alkyl, etc.; (2) a group represented by the formula: wherein Ris lower alkyl, etc.; (3) a group represented by the formula: wherein Ris lower alkyl, etc.; or (4) a group selected from halogen atom, carboxy, hydroxy and lower alkoxy, or a salt thereof.</description><language>eng</language><creationdate>2012</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8173684$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,776,798,881,64015</link.rule.ids><linktorsrc>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8173684$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Kasahara, Chiyoshi</creatorcontrib><creatorcontrib>Yamazaki, Hitoshi</creatorcontrib><creatorcontrib>Astellas Pharma Inc</creatorcontrib><creatorcontrib>Wakunaga Pharmaceutical Co., Ltd</creatorcontrib><title>Pyridone derivatives as p38α MAPK inhibitors</title><description>1 2 3 4 5 6 A compound represented by the formula (I): wherein Ris lower alkyl, cycloalkyl or aromatic hydrocarbon ring, each of which is optionally substituted with one or more substituents; 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Ris hydrogen atom, halogen atom, lower alkyl, halo(lower)alkyl or lower alkoxy; and Ris (1) a group represented by the formula: wherein Ris lower alkyl, etc.; (2) a group represented by the formula: wherein Ris lower alkyl, etc.; (3) a group represented by the formula: wherein Ris lower alkyl, etc.; or (4) a group selected from halogen atom, carboxy, hydroxy and lower alkoxy, or a salt thereof.</abstract><oa>free_for_read</oa></addata></record>
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title Pyridone derivatives as p38α MAPK inhibitors
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