Method for producing porous β-tricalcium phosphate granules

A porous β-tricalcium phosphate material for bone implantation is provided. The multiple pores in the porous TCP body are separate discrete voids and are not interconnected. The pore size diameter is in the range of 20-500 μm, preferably 50-125 μm. The porous β-TCP material provides a carrier matrix...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Dalal, Paresh S, Diamaano, Godofredo R, Kulkarni, Shailesh C
Format: Patent
Sprache:eng
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Dalal, Paresh S
Diamaano, Godofredo R
Kulkarni, Shailesh C
description A porous β-tricalcium phosphate material for bone implantation is provided. The multiple pores in the porous TCP body are separate discrete voids and are not interconnected. The pore size diameter is in the range of 20-500 μm, preferably 50-125 μm. The porous β-TCP material provides a carrier matrix for bioactive agents and can form a moldable putty composition upon the addition of a binder. Preferably, the bioactive agent is encapsulated in a biodegradable agent. The invention provides a kit and an implant device comprising the porous β-TCP, and a bioactive agent and a binder. The invention also provides an implantable prosthetic device comprising a prosthetic implant having a surface region, a porous β-TCP material disposed on the surface region and optionally comprising at least a bioactive agent or a binder. Methods of producing the porous β-TCP material and inducing bone formation are also provided.
format Patent
fullrecord <record><control><sourceid>uspatents_EFH</sourceid><recordid>TN_cdi_uspatents_grants_08173149</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>08173149</sourcerecordid><originalsourceid>FETCH-uspatents_grants_081731493</originalsourceid><addsrcrecordid>eNrjZLDxTS3JyE9RSMsvUigoyk8pTc7MS1coyC_KLy1WOLdJt6QoMzkxJzmzNFehICO_uCAjsSRVIb0oMa80J7WYh4E1LTGnOJUXSnMzKLi5hjh76JYWFwDV5ZUUx4OUAikDC0NzY0MTS2MilAAAPlEx9Q</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Method for producing porous β-tricalcium phosphate granules</title><source>USPTO Issued Patents</source><creator>Dalal, Paresh S ; Diamaano, Godofredo R ; Kulkarni, Shailesh C</creator><creatorcontrib>Dalal, Paresh S ; Diamaano, Godofredo R ; Kulkarni, Shailesh C ; Stryker Corporation</creatorcontrib><description>A porous β-tricalcium phosphate material for bone implantation is provided. The multiple pores in the porous TCP body are separate discrete voids and are not interconnected. The pore size diameter is in the range of 20-500 μm, preferably 50-125 μm. The porous β-TCP material provides a carrier matrix for bioactive agents and can form a moldable putty composition upon the addition of a binder. Preferably, the bioactive agent is encapsulated in a biodegradable agent. The invention provides a kit and an implant device comprising the porous β-TCP, and a bioactive agent and a binder. The invention also provides an implantable prosthetic device comprising a prosthetic implant having a surface region, a porous β-TCP material disposed on the surface region and optionally comprising at least a bioactive agent or a binder. Methods of producing the porous β-TCP material and inducing bone formation are also provided.</description><language>eng</language><creationdate>2012</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8173149$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,780,802,885,64039</link.rule.ids><linktorsrc>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8173149$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Dalal, Paresh S</creatorcontrib><creatorcontrib>Diamaano, Godofredo R</creatorcontrib><creatorcontrib>Kulkarni, Shailesh C</creatorcontrib><creatorcontrib>Stryker Corporation</creatorcontrib><title>Method for producing porous β-tricalcium phosphate granules</title><description>A porous β-tricalcium phosphate material for bone implantation is provided. The multiple pores in the porous TCP body are separate discrete voids and are not interconnected. The pore size diameter is in the range of 20-500 μm, preferably 50-125 μm. The porous β-TCP material provides a carrier matrix for bioactive agents and can form a moldable putty composition upon the addition of a binder. Preferably, the bioactive agent is encapsulated in a biodegradable agent. The invention provides a kit and an implant device comprising the porous β-TCP, and a bioactive agent and a binder. The invention also provides an implantable prosthetic device comprising a prosthetic implant having a surface region, a porous β-TCP material disposed on the surface region and optionally comprising at least a bioactive agent or a binder. Methods of producing the porous β-TCP material and inducing bone formation are also provided.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2012</creationdate><recordtype>patent</recordtype><sourceid>EFH</sourceid><recordid>eNrjZLDxTS3JyE9RSMsvUigoyk8pTc7MS1coyC_KLy1WOLdJt6QoMzkxJzmzNFehICO_uCAjsSRVIb0oMa80J7WYh4E1LTGnOJUXSnMzKLi5hjh76JYWFwDV5ZUUx4OUAikDC0NzY0MTS2MilAAAPlEx9Q</recordid><startdate>20120508</startdate><enddate>20120508</enddate><creator>Dalal, Paresh S</creator><creator>Diamaano, Godofredo R</creator><creator>Kulkarni, Shailesh C</creator><scope>EFH</scope></search><sort><creationdate>20120508</creationdate><title>Method for producing porous β-tricalcium phosphate granules</title><author>Dalal, Paresh S ; Diamaano, Godofredo R ; Kulkarni, Shailesh C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_grants_081731493</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2012</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Dalal, Paresh S</creatorcontrib><creatorcontrib>Diamaano, Godofredo R</creatorcontrib><creatorcontrib>Kulkarni, Shailesh C</creatorcontrib><creatorcontrib>Stryker Corporation</creatorcontrib><collection>USPTO Issued Patents</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Dalal, Paresh S</au><au>Diamaano, Godofredo R</au><au>Kulkarni, Shailesh C</au><aucorp>Stryker Corporation</aucorp><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Method for producing porous β-tricalcium phosphate granules</title><date>2012-05-08</date><risdate>2012</risdate><abstract>A porous β-tricalcium phosphate material for bone implantation is provided. The multiple pores in the porous TCP body are separate discrete voids and are not interconnected. The pore size diameter is in the range of 20-500 μm, preferably 50-125 μm. The porous β-TCP material provides a carrier matrix for bioactive agents and can form a moldable putty composition upon the addition of a binder. Preferably, the bioactive agent is encapsulated in a biodegradable agent. The invention provides a kit and an implant device comprising the porous β-TCP, and a bioactive agent and a binder. The invention also provides an implantable prosthetic device comprising a prosthetic implant having a surface region, a porous β-TCP material disposed on the surface region and optionally comprising at least a bioactive agent or a binder. Methods of producing the porous β-TCP material and inducing bone formation are also provided.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_uspatents_grants_08173149
source USPTO Issued Patents
title Method for producing porous β-tricalcium phosphate granules
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T14%3A30%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-uspatents_EFH&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Dalal,%20Paresh%20S&rft.aucorp=Stryker%20Corporation&rft.date=2012-05-08&rft_id=info:doi/&rft_dat=%3Cuspatents_EFH%3E08173149%3C/uspatents_EFH%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true