Fused heterocyclic compounds
1 2 33 12 3 12 3 244441-4 4 There is provided a CRF receptor antagonist comprising a compound of the formula (I): wherein Ris an optionally substituted hydrocarbyl, an optionally substituted C-linked heterocyclic group, an optionally substituted N-linked heteroaryl group, a cyano or an acyl; Ris an...
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creator | Aso, Kazuyoshi Mochizuki, Michiyo Gyorkos, Albert Charles Corrette, Christopher Peter Cho, Suk Young Pratt, Scott Alan Siedem, Christopher Stephen |
description | 1 2 33 12 3 12 3 244441-4 4 There is provided a CRF receptor antagonist comprising a compound of the formula (I): wherein Ris an optionally substituted hydrocarbyl, an optionally substituted C-linked heterocyclic group, an optionally substituted N-linked heteroaryl group, a cyano or an acyl; Ris an optionally substituted cyclic hydrocarbyl or an optionally substituted heterocyclic group; X is oxygen, sulfur or -NR- (wherein Ris a hydrogen, an optionally substituted hydrocarbyl or an acyl); Y, Yand Yare each an optionally substituted carbon or a nitrogen, provided that one or less of Y, Yand Yis nitrogen; and Z is a bond, -CO-, oxygen, sulfur, -SO-, -SO-, -NR-, -NR-alk-, -CONR- or -NRCO- (wherein alk is an optionally substituted Calkylene and Ris a hydrogen, an optionally substituted hydrocarbyl or an acyl); or a salt thereof or a prodrug thereof. |
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Takeda Pharmaceutical Company Limited</creatorcontrib><description>1 2 33 12 3 12 3 244441-4 4 There is provided a CRF receptor antagonist comprising a compound of the formula (I): wherein Ris an optionally substituted hydrocarbyl, an optionally substituted C-linked heterocyclic group, an optionally substituted N-linked heteroaryl group, a cyano or an acyl; Ris an optionally substituted cyclic hydrocarbyl or an optionally substituted heterocyclic group; X is oxygen, sulfur or -NR- (wherein Ris a hydrogen, an optionally substituted hydrocarbyl or an acyl); Y, Yand Yare each an optionally substituted carbon or a nitrogen, provided that one or less of Y, Yand Yis nitrogen; and Z is a bond, -CO-, oxygen, sulfur, -SO-, -SO-, -NR-, -NR-alk-, -CONR- or -NRCO- (wherein alk is an optionally substituted Calkylene and Ris a hydrogen, an optionally substituted hydrocarbyl or an acyl); or a salt thereof or a prodrug thereof.</description><language>eng</language><creationdate>2012</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8163935$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,780,802,885,64039</link.rule.ids><linktorsrc>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8163935$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Aso, Kazuyoshi</creatorcontrib><creatorcontrib>Mochizuki, Michiyo</creatorcontrib><creatorcontrib>Gyorkos, Albert Charles</creatorcontrib><creatorcontrib>Corrette, Christopher Peter</creatorcontrib><creatorcontrib>Cho, Suk Young</creatorcontrib><creatorcontrib>Pratt, Scott Alan</creatorcontrib><creatorcontrib>Siedem, Christopher Stephen</creatorcontrib><creatorcontrib>Takeda Pharmaceutical Company Limited</creatorcontrib><title>Fused heterocyclic compounds</title><description>1 2 33 12 3 12 3 244441-4 4 There is provided a CRF receptor antagonist comprising a compound of the formula (I): wherein Ris an optionally substituted hydrocarbyl, an optionally substituted C-linked heterocyclic group, an optionally substituted N-linked heteroaryl group, a cyano or an acyl; Ris an optionally substituted cyclic hydrocarbyl or an optionally substituted heterocyclic group; X is oxygen, sulfur or -NR- (wherein Ris a hydrogen, an optionally substituted hydrocarbyl or an acyl); Y, Yand Yare each an optionally substituted carbon or a nitrogen, provided that one or less of Y, Yand Yis nitrogen; and Z is a bond, -CO-, oxygen, sulfur, -SO-, -SO-, -NR-, -NR-alk-, -CONR- or -NRCO- (wherein alk is an optionally substituted Calkylene and Ris a hydrogen, an optionally substituted hydrocarbyl or an acyl); or a salt thereof or a prodrug thereof.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2012</creationdate><recordtype>patent</recordtype><sourceid>EFH</sourceid><recordid>eNrjZJBxKy1OTVHISC1JLcpPrkzOyUxWSM7PLcgvzUsp5mFgTUvMKU7lhdLcDApuriHOHrqlxQWJJal5JcXx6UWJIMrAwtDM2NLY1JgIJQCkhyUE</recordid><startdate>20120424</startdate><enddate>20120424</enddate><creator>Aso, Kazuyoshi</creator><creator>Mochizuki, Michiyo</creator><creator>Gyorkos, Albert Charles</creator><creator>Corrette, Christopher Peter</creator><creator>Cho, Suk Young</creator><creator>Pratt, Scott Alan</creator><creator>Siedem, Christopher Stephen</creator><scope>EFH</scope></search><sort><creationdate>20120424</creationdate><title>Fused heterocyclic compounds</title><author>Aso, Kazuyoshi ; Mochizuki, Michiyo ; Gyorkos, Albert Charles ; Corrette, Christopher Peter ; Cho, Suk Young ; Pratt, Scott Alan ; Siedem, Christopher Stephen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_grants_081639353</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2012</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Aso, Kazuyoshi</creatorcontrib><creatorcontrib>Mochizuki, Michiyo</creatorcontrib><creatorcontrib>Gyorkos, Albert Charles</creatorcontrib><creatorcontrib>Corrette, Christopher Peter</creatorcontrib><creatorcontrib>Cho, Suk Young</creatorcontrib><creatorcontrib>Pratt, Scott Alan</creatorcontrib><creatorcontrib>Siedem, Christopher Stephen</creatorcontrib><creatorcontrib>Takeda Pharmaceutical Company Limited</creatorcontrib><collection>USPTO Issued Patents</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Aso, Kazuyoshi</au><au>Mochizuki, Michiyo</au><au>Gyorkos, Albert Charles</au><au>Corrette, Christopher Peter</au><au>Cho, Suk Young</au><au>Pratt, Scott Alan</au><au>Siedem, Christopher Stephen</au><aucorp>Takeda Pharmaceutical Company Limited</aucorp><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Fused heterocyclic compounds</title><date>2012-04-24</date><risdate>2012</risdate><abstract>1 2 33 12 3 12 3 244441-4 4 There is provided a CRF receptor antagonist comprising a compound of the formula (I): wherein Ris an optionally substituted hydrocarbyl, an optionally substituted C-linked heterocyclic group, an optionally substituted N-linked heteroaryl group, a cyano or an acyl; Ris an optionally substituted cyclic hydrocarbyl or an optionally substituted heterocyclic group; X is oxygen, sulfur or -NR- (wherein Ris a hydrogen, an optionally substituted hydrocarbyl or an acyl); Y, Yand Yare each an optionally substituted carbon or a nitrogen, provided that one or less of Y, Yand Yis nitrogen; and Z is a bond, -CO-, oxygen, sulfur, -SO-, -SO-, -NR-, -NR-alk-, -CONR- or -NRCO- (wherein alk is an optionally substituted Calkylene and Ris a hydrogen, an optionally substituted hydrocarbyl or an acyl); or a salt thereof or a prodrug thereof.</abstract><oa>free_for_read</oa></addata></record> |
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title | Fused heterocyclic compounds |
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