Purification and characterization of cytotoxic lymphocyte maturation factor and monoclonal antibodies thereto

The present invention is a novel cytokine protein called IL-12 or Cytotoxic Lymphocyte Maturation Factor (CLMF) which is produced and synthesized by human NC-37 B lymphoblastoid cells (American Type Culture Collection, Rockville, Md.). CLMF synergistically induces with low concentrations of IL-2 the...

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Bibliographische Detailangaben

Hauptverfasser:	Gately, Maurice Kent, Gubler, Ulrich Andreas, Hulmes, Jeffrey David, Podlaski, Frank John, Stern, Alvin Seth, Chizzonite, Richard Anthony, Pan, Yu-Ching Eugene
Format:	Patent
Sprache:	eng
Online-Zugang:	Volltext bestellen
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