Method of producing microbial transglutaminase

Method of producing microbial transglutaminase

The present invention provides a neutral metalloprotease from actinomycetes which selectively cleaves a pro-structure part of a microbial protransglutaminase and a gene encoding said neutral metalloprotease. An active microbial transglutaminase having the pro-structure part cleaved can be obtained b...

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Hauptverfasser: Umezawa, Yukiko, Yokoyama, Keiichi, Kikuchi, Yoshimi, Date, Masayo, Onishi, Norimasa
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Sprache:eng
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creator Umezawa, Yukiko
Yokoyama, Keiichi
Kikuchi, Yoshimi
Date, Masayo
Onishi, Norimasa
description The present invention provides a neutral metalloprotease from actinomycetes which selectively cleaves a pro-structure part of a microbial protransglutaminase and a gene encoding said neutral metalloprotease. An active microbial transglutaminase having the pro-structure part cleaved can be obtained by culturing a microorganism into which a gene encoding the neutral metalloprotease from actinomycetes according to the present invention has been introduced, where by producing the neutral metalloprotease from actinomycetes, and reacting it on a microbial protransglutaminase.
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title Method of producing microbial transglutaminase
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