Systems and methods for measurement of objects of interest in medical images

A system and method are provided for the measurement and display of attributes of an object of interest in a medical image. An object of interest is identified, such as a lesion or cluster of lesions in a breast area on a mammography image. At least one attribute of the lesion is then automatically measured, such as the area of the lesion, the width and height of a cluster of lesions, the number of lesions in a cluster, or the distance from one or more lesions to an anatomical feature such as the nipple, skin line or chest wall. The measurements are then displayed to a user, for example by displaying the measurements on the mammography image. Additionally, anatomical zones, such as standard, quadrant and clock zones of the breast area may be determined and displayed on the mammography image or diagram to display the location of the lesion as it corresponds to the zones.