based oral vaccines for anthrax

Salmonella Salmonella A vaccine for the prevention of anthrax, including a live, attenuated and at least one nucleotide sequence encoding anthrax protective antigen (PA) or a fragment thereof and a nonlethal mutated form of anthrax lethal factor (LF) or a fragment thereof. In another implementation,...

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Bibliographische Detailangaben
1. Verfasser: Baillie, Leslie W. J
Format: Patent
Sprache:eng
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Zusammenfassung:Salmonella Salmonella A vaccine for the prevention of anthrax, including a live, attenuated and at least one nucleotide sequence encoding anthrax protective antigen (PA) or a fragment thereof and a nonlethal mutated form of anthrax lethal factor (LF) or a fragment thereof. In another implementation, the vaccine is constituted for the prevention of anthrax and at least one additional pathogen, as including a live, attenuated and at least one nucleotide sequence encoding at least a fragment of a nonlethal mutated form of anthrax lethal factor (LF) and at least one nucleotide sequence encoding at least a fragment of an antigen of an additional pathogen. Vaccines of such types can be administered to stimulate antibody response in a subject, whereby the antibody response confers immunity to the subject.