Preparation of 2R,3S-N-isobutyl-N-(2-hydroxy-3-amino-4-phenylbutyl)-P-nitrobenzenesulfonylamide hydrochloride and other derivatives of 2-hydroxy-1,3-diamines

The present invention provides a new process for the preparation of 2R,3S-N-isobutyl-N-(2-hydroxy-3-amino-4-phenylbuty1)-p-nitrobenzenesulfonylamide hydrochloride, wherein this compound is prepared directly from the chloromethylalcohol. Importantly, the process of the present invention results in hi...

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Bibliographische Detailangaben

Hauptverfasser:	Malik, Aslam A, Palandoken, Hasan, Stringer, Joy A, Carlson, Roland P, Leach, John, Archibald, Thomas G, Miotke, Robert G
Format:	Patent
Sprache:	eng
Online-Zugang:	Volltext bestellen
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