Method of identifying a chemical entity which is a hydroxylase modulator

A method of identifying, screening, characterising or designing a chemical entity, which mimics or binds to FIH, is described. The method comprises comparing a structural model of FIH with a structural model for said chemical entity, wherein said structural model of FIH is derived from structural fa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ratcliffe, Peter John, Pugh, Christopher William, Schofield, Christopher Joseph, Hewitson, Kirsty Sarah, Elkins, Jonathan Mark
Format: Patent
Sprache:eng
Online-Zugang:Volltext bestellen
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