Stereoselective alkylation of chiral 2-methyl-4-protected piperazines

Stereoselective alkylation of chiral 2-methyl-4-protected piperazines

In an illustrative embodiment, the present invention describes the synthesis of the following compound and similar compounds, in high stereochemical purity by a novel stereoselective alkylation process:

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Bibliographische Detailangaben
Hauptverfasser: Wu, Wenxue, Liao, Hongbiao, Tsai, David J, Andrews, David R, Gala, Dinesh, Lee, Gary M, Schwartz, Martin Lawrence, McAllister, Timothy L, Fu, Xiaoyong, Maloney, Donal, Thiruvengadam, Tiruvettipuram K, Tann, Chou-Hang
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:In an illustrative embodiment, the present invention describes the synthesis of the following compound and similar compounds, in high stereochemical purity by a novel stereoselective alkylation process: