Apparatus and method for assaying coagulation in fluid samples

Apparatus and method for assaying coagulation in fluid samples

This invention is a disposable cartridge for use at the patient side to perform traditional coagulation assays on fresh whole blood or blood derivative samples. The cartridge, in use with an electronic analyzer allows a fluid sample to be metered and quantitatively mixed with reagents which activate...

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Hauptverfasser: Opalsky, Cindra A. Widrig, Opalsky, David, Maczuszenko, Andrezej, Lauks, Imants R, Cheadle, Rhonda J
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Sprache:eng
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creator Opalsky, Cindra A. Widrig
Opalsky, David
Maczuszenko, Andrezej
Lauks, Imants R
Cheadle, Rhonda J
description This invention is a disposable cartridge for use at the patient side to perform traditional coagulation assays on fresh whole blood or blood derivative samples. The cartridge, in use with an electronic analyzer allows a fluid sample to be metered and quantitatively mixed with reagents which activate the coagulation cascade. An artificial substrate for thrombin, the enzyme whose action results in clot formation is also provided. Clot formation is subsequently detected using a microfabricated sensor also housed within the cartridge which detects electrochemically the product of the thrombin reaction upon the synthetic substrate.
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title Apparatus and method for assaying coagulation in fluid samples
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