System for and method of positioning cells and determining cellular activity thereof

System for and method of positioning cells and determining cellular activity thereof

A device for positioning at least one cell in at least one addressable position, the device comprising a substrate formed with at least one addressable pore and at least one channel embedded in the substrate and being held in fluid communication with the at least one pore. The at least one pore and...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Ben-Jacob, Eshel, Segev, Ronen, Baruchi, Itay, Hulata, Eyal, Shapira, Yoash, Hanein, Yael, Gabay, Tamir
Format: Patent
Sprache:eng
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Ben-Jacob, Eshel
Segev, Ronen
Baruchi, Itay
Hulata, Eyal
Shapira, Yoash
Hanein, Yael
Gabay, Tamir
description A device for positioning at least one cell in at least one addressable position, the device comprising a substrate formed with at least one addressable pore and at least one channel embedded in the substrate and being held in fluid communication with the at least one pore. The at least one pore and the at least one channel are designed and constructed such that an under-pressure formed in the at least one channel results in vacuum adherence of the at least one cell onto the at least one pore, such that a single cell is vacuum adhered onto a single pore. In one embodiment, the substrate is a non-conductive substrate and is further formed with one or more electrode structures, where each of the electrode structures is positioned in one of the pores. In an additional embodiment the device is designed to be locatable on an organ, such as the brain.
format Patent
fullrecord <record><control><sourceid>uspatents_EFH</sourceid><recordid>TN_cdi_uspatents_grants_07684844</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>07684844</sourcerecordid><originalsourceid>FETCH-uspatents_grants_076848443</originalsourceid><addsrcrecordid>eNqNi8sKwjAQRbNxIeo_zA8IgkG7F8W93cvQTNqBJFMyU6F_7wNx7erAPfcsXXub1ShDlApYAmSyQQJIhFGUjaVw6aGjlPTjAxnVzL91SvgKO-MH2ww2UCWJa7eImJQ2X64cXM7t6bqddESjYnrvK76xOx4a33i__-PyBHeYOi0</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>System for and method of positioning cells and determining cellular activity thereof</title><source>USPTO Issued Patents</source><creator>Ben-Jacob, Eshel ; Segev, Ronen ; Baruchi, Itay ; Hulata, Eyal ; Shapira, Yoash ; Hanein, Yael ; Gabay, Tamir</creator><creatorcontrib>Ben-Jacob, Eshel ; Segev, Ronen ; Baruchi, Itay ; Hulata, Eyal ; Shapira, Yoash ; Hanein, Yael ; Gabay, Tamir ; Ramot at Tel Aviv University Ltd</creatorcontrib><description>A device for positioning at least one cell in at least one addressable position, the device comprising a substrate formed with at least one addressable pore and at least one channel embedded in the substrate and being held in fluid communication with the at least one pore. The at least one pore and the at least one channel are designed and constructed such that an under-pressure formed in the at least one channel results in vacuum adherence of the at least one cell onto the at least one pore, such that a single cell is vacuum adhered onto a single pore. In one embodiment, the substrate is a non-conductive substrate and is further formed with one or more electrode structures, where each of the electrode structures is positioned in one of the pores. In an additional embodiment the device is designed to be locatable on an organ, such as the brain.</description><language>eng</language><creationdate>2010</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7684844$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,776,798,881,64015</link.rule.ids><linktorsrc>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7684844$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Ben-Jacob, Eshel</creatorcontrib><creatorcontrib>Segev, Ronen</creatorcontrib><creatorcontrib>Baruchi, Itay</creatorcontrib><creatorcontrib>Hulata, Eyal</creatorcontrib><creatorcontrib>Shapira, Yoash</creatorcontrib><creatorcontrib>Hanein, Yael</creatorcontrib><creatorcontrib>Gabay, Tamir</creatorcontrib><creatorcontrib>Ramot at Tel Aviv University Ltd</creatorcontrib><title>System for and method of positioning cells and determining cellular activity thereof</title><description>A device for positioning at least one cell in at least one addressable position, the device comprising a substrate formed with at least one addressable pore and at least one channel embedded in the substrate and being held in fluid communication with the at least one pore. The at least one pore and the at least one channel are designed and constructed such that an under-pressure formed in the at least one channel results in vacuum adherence of the at least one cell onto the at least one pore, such that a single cell is vacuum adhered onto a single pore. In one embodiment, the substrate is a non-conductive substrate and is further formed with one or more electrode structures, where each of the electrode structures is positioned in one of the pores. In an additional embodiment the device is designed to be locatable on an organ, such as the brain.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2010</creationdate><recordtype>patent</recordtype><sourceid>EFH</sourceid><recordid>eNqNi8sKwjAQRbNxIeo_zA8IgkG7F8W93cvQTNqBJFMyU6F_7wNx7erAPfcsXXub1ShDlApYAmSyQQJIhFGUjaVw6aGjlPTjAxnVzL91SvgKO-MH2ww2UCWJa7eImJQ2X64cXM7t6bqddESjYnrvK76xOx4a33i__-PyBHeYOi0</recordid><startdate>20100323</startdate><enddate>20100323</enddate><creator>Ben-Jacob, Eshel</creator><creator>Segev, Ronen</creator><creator>Baruchi, Itay</creator><creator>Hulata, Eyal</creator><creator>Shapira, Yoash</creator><creator>Hanein, Yael</creator><creator>Gabay, Tamir</creator><scope>EFH</scope></search><sort><creationdate>20100323</creationdate><title>System for and method of positioning cells and determining cellular activity thereof</title><author>Ben-Jacob, Eshel ; Segev, Ronen ; Baruchi, Itay ; Hulata, Eyal ; Shapira, Yoash ; Hanein, Yael ; Gabay, Tamir</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_grants_076848443</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2010</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Ben-Jacob, Eshel</creatorcontrib><creatorcontrib>Segev, Ronen</creatorcontrib><creatorcontrib>Baruchi, Itay</creatorcontrib><creatorcontrib>Hulata, Eyal</creatorcontrib><creatorcontrib>Shapira, Yoash</creatorcontrib><creatorcontrib>Hanein, Yael</creatorcontrib><creatorcontrib>Gabay, Tamir</creatorcontrib><creatorcontrib>Ramot at Tel Aviv University Ltd</creatorcontrib><collection>USPTO Issued Patents</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Ben-Jacob, Eshel</au><au>Segev, Ronen</au><au>Baruchi, Itay</au><au>Hulata, Eyal</au><au>Shapira, Yoash</au><au>Hanein, Yael</au><au>Gabay, Tamir</au><aucorp>Ramot at Tel Aviv University Ltd</aucorp><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>System for and method of positioning cells and determining cellular activity thereof</title><date>2010-03-23</date><risdate>2010</risdate><abstract>A device for positioning at least one cell in at least one addressable position, the device comprising a substrate formed with at least one addressable pore and at least one channel embedded in the substrate and being held in fluid communication with the at least one pore. The at least one pore and the at least one channel are designed and constructed such that an under-pressure formed in the at least one channel results in vacuum adherence of the at least one cell onto the at least one pore, such that a single cell is vacuum adhered onto a single pore. In one embodiment, the substrate is a non-conductive substrate and is further formed with one or more electrode structures, where each of the electrode structures is positioned in one of the pores. In an additional embodiment the device is designed to be locatable on an organ, such as the brain.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_uspatents_grants_07684844
source USPTO Issued Patents
title System for and method of positioning cells and determining cellular activity thereof
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-28T01%3A52%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-uspatents_EFH&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Ben-Jacob,%20Eshel&rft.aucorp=Ramot%20at%20Tel%20Aviv%20University%20Ltd&rft.date=2010-03-23&rft_id=info:doi/&rft_dat=%3Cuspatents_EFH%3E07684844%3C/uspatents_EFH%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true