Recombinant BCG vaccine

Recombinant BCG vaccine

A recombinant BCG vaccine being transformed with an expression vector that has a polynucleotide encoding a foreign antigenic protein, wherein the polynucleotide is a modified one in which the third position of each codon is substituted with G or C without a change of an amino acid. This recombinant...

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Hauptverfasser: Honda, Mitsuo, Matsuo, Kazuhiro, Kanekiyo, Masaru, Promkhatkaew, Duanthanorm
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creator Honda, Mitsuo
Matsuo, Kazuhiro
Kanekiyo, Masaru
Promkhatkaew, Duanthanorm
description A recombinant BCG vaccine being transformed with an expression vector that has a polynucleotide encoding a foreign antigenic protein, wherein the polynucleotide is a modified one in which the third position of each codon is substituted with G or C without a change of an amino acid. This recombinant BCG vaccine has an excellent expression rate of antigenic protein and, as a result, capable of inducing a sufficient immune response against target infectious disease, cancer, or the like at the same dose as that of the typical BCG vaccine.
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title Recombinant BCG vaccine
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