Outer membrane vesicles and uses thereof

The present invention discloses a Gram negative bacterium in which the expression of a protein involved in LPS transport to the outer membrane is functionally downregulated such that the level of LPS in the outer membrane is decreased compared to a wild-type Gram negative bacterium. Down regulation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bos, Martine Petronella, Poolman, Jan, Tefsen, Boris, Tommassen, Johannes Petrus Maria
Format: Patent
Sprache:eng
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