Carbamic acid compounds comprising an amide linkage as HDAC inhibitors

This invention pertains to certain active carbamic acid compounds which inhibit HDAC activity and which have the formula (1) wherein: A is an aryl group; Q1 is an aryl leader group having a backbone of at least 2 carbon atoms; J is an amide linkage selected from: -NR1C(═O)- and -C(═O)NR1-; R1 is an...

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Hauptverfasser: Watkins, Clare J, Romero-Martin, Maria Rosario, Moore, Kathryn G, Ritchie, James, Finn, Paul W, Kalvinsh, Ivars, Loza, Einars, Starchenkov, Igor, Dikovska, Klara, Bokaldere, Rasma M, Gailite, Vija, Vorona, Maxim, Andrianov, Victor, Lolya, Daina, Semenikhina, Valentina, Amolins, Andris, Harris, C. John, Duffy, James E. S
Format: Patent
Sprache:eng
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