Process for the preparation of biphosphonic derivatives
353335 The present invention provides a novel process for preparation of bisphosphonic acid derivatives or pharmaceutical acceptable salt thereof, by reacting carboxylic acid having structural formula (II) with phosphorous acid and a halophosphorous compound, wherein halophosphorous compound is sele...
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| Format: | Patent |
| Sprache: | eng |
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| Zusammenfassung: | 353335 The present invention provides a novel process for preparation of bisphosphonic acid derivatives or pharmaceutical acceptable salt thereof, by reacting carboxylic acid having structural formula (II) with phosphorous acid and a halophosphorous compound, wherein halophosphorous compound is selected from the group comprising of PCl, PCl, POCl, PBr, POBr, and PBrin presence of diphenyl ether. |
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