Synthesis of polyanhydrides

1211 2 The present invention provides a method for forming compounds of Formula HO-C(═O)R-X-R-X-R-C(═O)-O-H wherein compound (I) can be polymerized to provide a polymer that contains therapeutically active compounds. In the compounds of the invention, each Ris group that will provide the therapeutic...

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Bibliographische Detailangaben
Hauptverfasser: Uhrich, Kathryn E, Schmeltzer, Robert C, Anastasiou, Theodore James
Format: Patent
Sprache:eng
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Zusammenfassung:1211 2 The present invention provides a method for forming compounds of Formula HO-C(═O)R-X-R-X-R-C(═O)-O-H wherein compound (I) can be polymerized to provide a polymer that contains therapeutically active compounds. In the compounds of the invention, each Ris group that will provide the therapeutically active compound upon hydrolysis of the polymer; each X is independently an ester linkage or an amide linkage; and Ris a linking group.