Automated immunoassay cassette, apparatus and method

Automated immunoassay cassette, apparatus and method

An immunoassay cassette, apparatus, and method for detecting an analyte in a liquid body-fluid sample are disclosed. The cassette has a body and a support mounted on the body, for movement relative to the body to first and second transfer positions. Sample supplied to a sample well in the cassette b...

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Hauptverfasser: Bellet, Neal F, Shindelman, Jeffrey, Worthy, Thomas E, Haley, Kimberly, Lee, Richard K-T, Kyung, Jane Eunhee, Qian, Suyue
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Sprache:eng
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creator Bellet, Neal F
Shindelman, Jeffrey
Worthy, Thomas E
Haley, Kimberly
Lee, Richard K-T
Kyung, Jane Eunhee
Qian, Suyue
description An immunoassay cassette, apparatus, and method for detecting an analyte in a liquid body-fluid sample are disclosed. The cassette has a body and a support mounted on the body, for movement relative to the body to first and second transfer positions. Sample supplied to a sample well in the cassette body is transferred to a reagent reservoir on the cassette body, by moving the support to its first transfer position. Here the sample reacts with a first reagent composition in the reservoir effective to form a modified sample. The modified sample is then transferred to a reagent strip on the support by moving the support to its second transfer position. The reagent strip has a transfer zone at which sample material is transferred to the strip, a second reagent composition effective to react with the modified sample to form a detectable analyte-dependent product, and a detection zone located downstream at which the detectable product can be observed. By controlling movement of the support to its first and second positions, the cassette can effectively handle a variety of samples having different flow rates.
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title Automated immunoassay cassette, apparatus and method
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