Acetylenic aryl sulfonate hydroxamic acid TACE and matrix metalloproteinase inhibitors

Acetylenic aryl sulfonate hydroxamic acid TACE and matrix metalloproteinase inhibitors

Hydroxamic acids having the formula are useful in treating disease conditions mediated by TNF-□, such as rheumatoid arthritis, graft rejection, cachexia, inflammation, fever, insulin resistance, septic shock, congestive heart failure, inflammatory disease of the central nervous system, inflammatory...

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Hauptverfasser: Levin, Jeremy Ian, Du, Mila Ti
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Sprache:eng
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creator Levin, Jeremy Ian
Du, Mila Ti
description Hydroxamic acids having the formula are useful in treating disease conditions mediated by TNF-□, such as rheumatoid arthritis, graft rejection, cachexia, inflammation, fever, insulin resistance, septic shock, congestive heart failure, inflammatory disease of the central nervous system, inflammatory bowel disease or HIV infection.
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title Acetylenic aryl sulfonate hydroxamic acid TACE and matrix metalloproteinase inhibitors
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