Hypoglycaemic peptides and methods of use thereof
n11n21 A peptide of the formula (Xaa)-Xaa-His-Thr-Asp-(Xaa), wherein Xaa is any amino acid; Xaais a hydrophobic amino acid, preferably Gly or Val; n1 is 0-10; and n2 is 0-10; and use thereof in regulating in vivo blood glucose levels in a human or other mammal, particularly in the treatment of Type...
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| creator | Zimmet, Paul Zev Ng, Frank Man-Woon |
| description | n11n21 A peptide of the formula (Xaa)-Xaa-His-Thr-Asp-(Xaa), wherein Xaa is any amino acid; Xaais a hydrophobic amino acid, preferably Gly or Val; n1 is 0-10; and n2 is 0-10; and use thereof in regulating in vivo blood glucose levels in a human or other mammal, particularly in the treatment of Type 2 diabetes in a human. Preferably, the peptide is a tetrapeptide selected from Gly-His-Thr-Asp and Val-His-Thr-Asp. These hypoglycaemic peptides are isolated from human urine and they also have been chemically synthesized. |
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Preferably, the peptide is a tetrapeptide selected from Gly-His-Thr-Asp and Val-His-Thr-Asp. 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Preferably, the peptide is a tetrapeptide selected from Gly-His-Thr-Asp and Val-His-Thr-Asp. These hypoglycaemic peptides are isolated from human urine and they also have been chemically synthesized.</abstract><oa>free_for_read</oa></addata></record> |
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| title | Hypoglycaemic peptides and methods of use thereof |
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