Non-sedating barbituric acid derivatives

The present invention relates to novel non-sedating barbituric acid derivatives, pharmaceutical compositions containing them and methods of neuroprotection in cases of cerebral ischemia, head trauma and other acute neurologic injuries, and prevention of resulting neuronal damage. The invention also...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Gutman, Daniella, Moros, Daniel A
Format: Patent
Sprache:eng
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Gutman, Daniella
Moros, Daniel A
description The present invention relates to novel non-sedating barbituric acid derivatives, pharmaceutical compositions containing them and methods of neuroprotection in cases of cerebral ischemia, head trauma and other acute neurologic injuries, and prevention of resulting neuronal damage. The invention also relates to the use of non-sedating barbituric acid derivatives given in a manner and dosage effective to produce blood levels and brain levels of these drugs and/or their active metabolites sufficient to provide a therapeutic effect.
format Patent
fullrecord <record><control><sourceid>uspatents_EFH</sourceid><recordid>TN_cdi_uspatents_grants_06939873</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>06939873</sourcerecordid><originalsourceid>FETCH-uspatents_grants_069398733</originalsourceid><addsrcrecordid>eNrjZNDwy8_TLU5NSSzJzEtXSEosSsosKS3KTFZITM5MUUhJLcosA0qVpRbzMLCmJeYUp_JCaW4GBTfXEGcP3dLigsSS1LyS4vj0okQQZWBmaWxpYW5sTIQSAL0fKXw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Non-sedating barbituric acid derivatives</title><source>USPTO Issued Patents</source><creator>Gutman, Daniella ; Moros, Daniel A</creator><creatorcontrib>Gutman, Daniella ; Moros, Daniel A ; Taro Pharmaceuticals Industries Limited</creatorcontrib><description>The present invention relates to novel non-sedating barbituric acid derivatives, pharmaceutical compositions containing them and methods of neuroprotection in cases of cerebral ischemia, head trauma and other acute neurologic injuries, and prevention of resulting neuronal damage. The invention also relates to the use of non-sedating barbituric acid derivatives given in a manner and dosage effective to produce blood levels and brain levels of these drugs and/or their active metabolites sufficient to provide a therapeutic effect.</description><language>eng</language><creationdate>2005</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6939873$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,780,802,885,64037</link.rule.ids><linktorsrc>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6939873$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Gutman, Daniella</creatorcontrib><creatorcontrib>Moros, Daniel A</creatorcontrib><creatorcontrib>Taro Pharmaceuticals Industries Limited</creatorcontrib><title>Non-sedating barbituric acid derivatives</title><description>The present invention relates to novel non-sedating barbituric acid derivatives, pharmaceutical compositions containing them and methods of neuroprotection in cases of cerebral ischemia, head trauma and other acute neurologic injuries, and prevention of resulting neuronal damage. The invention also relates to the use of non-sedating barbituric acid derivatives given in a manner and dosage effective to produce blood levels and brain levels of these drugs and/or their active metabolites sufficient to provide a therapeutic effect.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2005</creationdate><recordtype>patent</recordtype><sourceid>EFH</sourceid><recordid>eNrjZNDwy8_TLU5NSSzJzEtXSEosSsosKS3KTFZITM5MUUhJLcosA0qVpRbzMLCmJeYUp_JCaW4GBTfXEGcP3dLigsSS1LyS4vj0okQQZWBmaWxpYW5sTIQSAL0fKXw</recordid><startdate>20050906</startdate><enddate>20050906</enddate><creator>Gutman, Daniella</creator><creator>Moros, Daniel A</creator><scope>EFH</scope></search><sort><creationdate>20050906</creationdate><title>Non-sedating barbituric acid derivatives</title><author>Gutman, Daniella ; Moros, Daniel A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_grants_069398733</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2005</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Gutman, Daniella</creatorcontrib><creatorcontrib>Moros, Daniel A</creatorcontrib><creatorcontrib>Taro Pharmaceuticals Industries Limited</creatorcontrib><collection>USPTO Issued Patents</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Gutman, Daniella</au><au>Moros, Daniel A</au><aucorp>Taro Pharmaceuticals Industries Limited</aucorp><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Non-sedating barbituric acid derivatives</title><date>2005-09-06</date><risdate>2005</risdate><abstract>The present invention relates to novel non-sedating barbituric acid derivatives, pharmaceutical compositions containing them and methods of neuroprotection in cases of cerebral ischemia, head trauma and other acute neurologic injuries, and prevention of resulting neuronal damage. The invention also relates to the use of non-sedating barbituric acid derivatives given in a manner and dosage effective to produce blood levels and brain levels of these drugs and/or their active metabolites sufficient to provide a therapeutic effect.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_uspatents_grants_06939873
source USPTO Issued Patents
title Non-sedating barbituric acid derivatives
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-13T18%3A22%3A02IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-uspatents_EFH&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Gutman,%20Daniella&rft.aucorp=Taro%20Pharmaceuticals%20Industries%20Limited&rft.date=2005-09-06&rft_id=info:doi/&rft_dat=%3Cuspatents_EFH%3E06939873%3C/uspatents_EFH%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true