Tetrahydroisoquinoline derivatives as melatonin MT2 antagonists

Tetrahydroisoquinoline derivatives as melatonin MT2 antagonists

2 The invention encompasses a series of tetrahydroisoquinolines of formula I which are antagonists of the human melatonin MTreceptor and are useful as chronobiotic and sleep agents.

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Bibliographische Detailangaben
Hauptverfasser: Dubowchik, Gene M, Ditta, Jonathan L, Bertenshaw, Stephen R
Format: Patent
Sprache:eng
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Zusammenfassung:2 The invention encompasses a series of tetrahydroisoquinolines of formula I which are antagonists of the human melatonin MTreceptor and are useful as chronobiotic and sleep agents.