Enantioselective bioreduction for the preparation of integrin receptor antagonist intermediates

The present invention relates to a bioreductive process for the efficient preparation of chiral allylic alcohol intermediates which are useful in the asymmetric synthesis of integrin v 3 receptor antagonists. The process comprises an enantioselective 1,2-reduction of a prochiral , -unsaturated keton...

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Hauptverfasser:	Sturr, Michael G, Boyd, Russell Fieldon, Gbewonyo, Kodzo, Nti-Gyabaah, Joseph, Pollard, David J, McWilliams, James Christopher, Telari, Kathleen A
Format:	Patent
Sprache:	eng
Online-Zugang:	Volltext bestellen
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