CDK inhibitors having 3-hydroxychromen-4-one structure

The present invention relates to a novel 3-hydroxychromen-4-one derivative represented by the following formula (1): A novel 3-hydroxychromen-4-one derivative, pharmaceutically acceptable salt, hydrate, solvate or isomer thereof which is useful as an inhibitor for Cyclin Dependent Kinase ("CDK&...

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Hauptverfasser: Hong, Chang-Yong, Lee, Jin-Ho, Park, Tae-Sik, Kim, Jong-Hyun, Choi, Sei-Hyun, Yoon, Sook-Kyung, Chung, Hyun-Ho, Son, Ho-Sun, Kim, Eunice Eun-Kyeong, Ro, Seong-Gu, Jeong, Shin-Wu, Kim, Dong-Myung
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creator Hong, Chang-Yong
Lee, Jin-Ho
Park, Tae-Sik
Kim, Jong-Hyun
Choi, Sei-Hyun
Yoon, Sook-Kyung
Chung, Hyun-Ho
Son, Ho-Sun
Kim, Eunice Eun-Kyeong
Ro, Seong-Gu
Jeong, Shin-Wu
Kim, Dong-Myung
description The present invention relates to a novel 3-hydroxychromen-4-one derivative represented by the following formula (1): A novel 3-hydroxychromen-4-one derivative, pharmaceutically acceptable salt, hydrate, solvate or isomer thereof which is useful as an inhibitor for Cyclin Dependent Kinase ("CDK") is disclosed. Further, a process for preparing the compound and a composition for suppression or treatment of cancer and diseases induced by cell proliferation such as inflammation, angiostenosis, angiogenesis, etc. is disclosed comprising the compound as an active component together with pharmaceutically acceptable carriers.
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title CDK inhibitors having 3-hydroxychromen-4-one structure
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