Method and apparatus for screening microscopic cells utilizing light scatter techniques

Method and apparatus for screening microscopic cells utilizing light scatter techniques

This invention relates generally to a method and apparatus for screening microscopic cells which express selected characteristics utilizing light scatter or light scatter and electronic sensing techniques. More particularly, the invention is directed to an analysis of one or more cell groups of inte...

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Hauptverfasser: Russell, Thomas, Hudson, James Carey, Coulter, Wallace H, Rodriguez, Carlos M, Hajek, Constance Mary
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Sprache:eng
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creator Russell, Thomas
Hudson, James Carey
Coulter, Wallace H
Rodriguez, Carlos M
Hajek, Constance Mary
description This invention relates generally to a method and apparatus for screening microscopic cells which express selected characteristics utilizing light scatter or light scatter and electronic sensing techniques. More particularly, the invention is directed to an analysis of one or more cell groups of interest obscured in a cell population by utilizing microspheres having monoclonal antibodies bound thereto to change the sensed characteristics of each specified cell to differentiate the cells of the cell group of interest from the cell population. A method for performing screening of one or more cell groups of interest obscured by a cell population such as one or more subsets of interest of a WBC population utilizing at least one light sensing parameter. The cell group of interest is enumerated by utilizing microspheres having monoclonal antibodies bound thereto to modify the sensed characteristics of specified cells to differentiate the cell group of interest from the obscuring cell population.
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title Method and apparatus for screening microscopic cells utilizing light scatter techniques
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