Metered dose inhaler for fluticasone propionate

Drugs for treating respiratory and nasal disorders are frequently administered in aerosol formulations through the mouth or nose. One widely used method for dispensing such aerosol drug formulations involves making a suspension formulation of the drug as a finely divided powder in a liquefied gas kn...

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Hauptverfasser: Ashurst, Ian C, Britto, Ignatius Loy, Herman, Craig Steven, Li-Bovet, Li, Riebe, Michael Thomas
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Sprache:eng
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creator Ashurst, Ian C
Britto, Ignatius Loy
Herman, Craig Steven
Li-Bovet, Li
Riebe, Michael Thomas
description Drugs for treating respiratory and nasal disorders are frequently administered in aerosol formulations through the mouth or nose. One widely used method for dispensing such aerosol drug formulations involves making a suspension formulation of the drug as a finely divided powder in a liquefied gas known as a propellant. The suspension is stored in a sealed container capable of withstanding the pressure required to maintain the propellant as a liquid. The suspension is dispersed by activation of a dose metering valve affixed to the container. A metered dose inhaler having all or part of its internal surfaces coated with one or more fluorocarbon polymers, optimally in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formation comprising albuterol or a physiologically acceptable salt thereof and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents or one or more excipients.
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title Metered dose inhaler for fluticasone propionate
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