Equine herpesvirus glycoproteins

This invention relates to Equine Herpesvirus and in particular to type-specific glycoproteins thereof and diagnostic tests and clinical applications associated with the characterization of such glycoproteins. A vaccine for the selective immunization of horses against EHV4 and/or EHV1 is provided com...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Crabb, Brendan Scott, Studdert, Michael Justin
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:This invention relates to Equine Herpesvirus and in particular to type-specific glycoproteins thereof and diagnostic tests and clinical applications associated with the characterization of such glycoproteins. A vaccine for the selective immunization of horses against EHV4 and/or EHV1 is provided comprising at least one of (i) EHV4 virus wherein a portion of the gG gene of the EHV4 virus that elicits a type-specific response to EHV4 has been deleted and (ii) EHV1 virus wherein a portion of the gG gene of the EHV1 virus that elicits a type-specific response to EHV1 has been deleted. Antibodies which specifically bind to a epitopes of EHV4 gG or EHV1 also are provided.