Genetic sequences related to Alzheimer's Disease
The present invention relates generally to the field of neurological and physiological disfunctions associated with Alzheimer's Disease. More particularly, the invention is concerned with the identification, isolation and cloning of the gene which when mutated is associated with Alzheimer'...
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| creator | St. George-Hyslop, Peter H Rommens, Johanna M Fraser, Paul E |
| description | The present invention relates generally to the field of neurological and physiological disfunctions associated with Alzheimer's Disease. More particularly, the invention is concerned with the identification, isolation and cloning of the gene which when mutated is associated with Alzheimer's Disease as well as its transcript, gene products and associated sequence information and neighbouring genes. The present invention also relates to methods of diagnosing for and detection of carriers of the gene, Alzheimer Disease diagnosis, gene therapy using recombinant technologies and therapy using the information derived from the DNA, protein, and the metabolic function of the protein.
The present invention relates to the identification, isolation and cloning of a mammalian polynucleotide which encodes a Alzheimer's related membrane protein (ARMP). The invention also contemplates mutant polynucleotides and polynucleotides that encode ARMP homologs. Vectors encoding the protein and host cells transfected with the vector are further contemplated by the present invention. |
| format | Patent |
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The present invention relates to the identification, isolation and cloning of a mammalian polynucleotide which encodes a Alzheimer's related membrane protein (ARMP). The invention also contemplates mutant polynucleotides and polynucleotides that encode ARMP homologs. Vectors encoding the protein and host cells transfected with the vector are further contemplated by the present invention.</description><language>eng</language><creationdate>2003</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6531586$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,776,798,881,64016</link.rule.ids><linktorsrc>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6531586$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>St. George-Hyslop, Peter H</creatorcontrib><creatorcontrib>Rommens, Johanna M</creatorcontrib><creatorcontrib>Fraser, Paul E</creatorcontrib><creatorcontrib>HSC Research and Development Limited Partnership</creatorcontrib><creatorcontrib>The Hospital for Sick Children</creatorcontrib><creatorcontrib>The Governing Council of the University of Toronto</creatorcontrib><title>Genetic sequences related to Alzheimer's Disease</title><description>The present invention relates generally to the field of neurological and physiological disfunctions associated with Alzheimer's Disease. More particularly, the invention is concerned with the identification, isolation and cloning of the gene which when mutated is associated with Alzheimer's Disease as well as its transcript, gene products and associated sequence information and neighbouring genes. The present invention also relates to methods of diagnosing for and detection of carriers of the gene, Alzheimer Disease diagnosis, gene therapy using recombinant technologies and therapy using the information derived from the DNA, protein, and the metabolic function of the protein.
The present invention relates to the identification, isolation and cloning of a mammalian polynucleotide which encodes a Alzheimer's related membrane protein (ARMP). The invention also contemplates mutant polynucleotides and polynucleotides that encode ARMP homologs. Vectors encoding the protein and host cells transfected with the vector are further contemplated by the present invention.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2003</creationdate><recordtype>patent</recordtype><sourceid>EFH</sourceid><recordid>eNrjZDBwT81LLclMVihOLSxNzUtOLVYoSs1JLElNUSjJV3DMqcpIzcxNLVIvVnDJLE5NLE7lYWBNS8wpTuWF0twMCm6uIc4euqXFBUBteSXF8elFiSDKwMzU2NDUwsyYCCUAHUgr8Q</recordid><startdate>20030311</startdate><enddate>20030311</enddate><creator>St. George-Hyslop, Peter H</creator><creator>Rommens, Johanna M</creator><creator>Fraser, Paul E</creator><scope>EFH</scope></search><sort><creationdate>20030311</creationdate><title>Genetic sequences related to Alzheimer's Disease</title><author>St. George-Hyslop, Peter H ; Rommens, Johanna M ; Fraser, Paul E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_grants_065315863</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2003</creationdate><toplevel>online_resources</toplevel><creatorcontrib>St. George-Hyslop, Peter H</creatorcontrib><creatorcontrib>Rommens, Johanna M</creatorcontrib><creatorcontrib>Fraser, Paul E</creatorcontrib><creatorcontrib>HSC Research and Development Limited Partnership</creatorcontrib><creatorcontrib>The Hospital for Sick Children</creatorcontrib><creatorcontrib>The Governing Council of the University of Toronto</creatorcontrib><collection>USPTO Issued Patents</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>St. George-Hyslop, Peter H</au><au>Rommens, Johanna M</au><au>Fraser, Paul E</au><aucorp>HSC Research and Development Limited Partnership</aucorp><aucorp>The Hospital for Sick Children</aucorp><aucorp>The Governing Council of the University of Toronto</aucorp><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Genetic sequences related to Alzheimer's Disease</title><date>2003-03-11</date><risdate>2003</risdate><abstract>The present invention relates generally to the field of neurological and physiological disfunctions associated with Alzheimer's Disease. More particularly, the invention is concerned with the identification, isolation and cloning of the gene which when mutated is associated with Alzheimer's Disease as well as its transcript, gene products and associated sequence information and neighbouring genes. The present invention also relates to methods of diagnosing for and detection of carriers of the gene, Alzheimer Disease diagnosis, gene therapy using recombinant technologies and therapy using the information derived from the DNA, protein, and the metabolic function of the protein.
The present invention relates to the identification, isolation and cloning of a mammalian polynucleotide which encodes a Alzheimer's related membrane protein (ARMP). The invention also contemplates mutant polynucleotides and polynucleotides that encode ARMP homologs. Vectors encoding the protein and host cells transfected with the vector are further contemplated by the present invention.</abstract><oa>free_for_read</oa></addata></record> |
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| title | Genetic sequences related to Alzheimer's Disease |
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