Lateral flow testing device with on-board chemical reactant
The present invention generally relates to a test device and method for testing a biological fluid for the presence of certain "drugs of abuse", and more specifically relates to a lateral flow testing device and method for testing for the presence of methamphetamines in a biological sample...
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| creator | Goodell, Raegan E Blevins, Dennis D |
| description | The present invention generally relates to a test device and method for testing a biological fluid for the presence of certain "drugs of abuse", and more specifically relates to a lateral flow testing device and method for testing for the presence of methamphetamines in a biological sample and the elimination of undesirable cross-reactivity to other substances that may be present in the sample.
A lateral flow testing device is provided for testing a biological fluid for the presence of methamphetamines. The device includes a substrate element such as a nitrocellulose strip, including an antibody zone and an immobilized drug conjugate zone for detecting presence of methamphetamines, and an on-board chemical reactant for preventing undesirable cross-reactivity to ephedrine and/or pseudoephedrine that may be present in the biological fluid being tested. Preferably, the on-board chemical reactant is sodium periodate. Methods for preparing test devices are provided including the step of striping a substrate sheet with a solution containing sodium periodate during manufacture of methamphetamine lateral flow test strips. |
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A lateral flow testing device is provided for testing a biological fluid for the presence of methamphetamines. The device includes a substrate element such as a nitrocellulose strip, including an antibody zone and an immobilized drug conjugate zone for detecting presence of methamphetamines, and an on-board chemical reactant for preventing undesirable cross-reactivity to ephedrine and/or pseudoephedrine that may be present in the biological fluid being tested. Preferably, the on-board chemical reactant is sodium periodate. Methods for preparing test devices are provided including the step of striping a substrate sheet with a solution containing sodium periodate during manufacture of methamphetamine lateral flow test strips.</description><language>eng</language><creationdate>2002</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6492127$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,780,802,885,64039</link.rule.ids><linktorsrc>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6492127$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Goodell, Raegan E</creatorcontrib><creatorcontrib>Blevins, Dennis D</creatorcontrib><creatorcontrib>Varian, Inc</creatorcontrib><title>Lateral flow testing device with on-board chemical reactant</title><description>The present invention generally relates to a test device and method for testing a biological fluid for the presence of certain "drugs of abuse", and more specifically relates to a lateral flow testing device and method for testing for the presence of methamphetamines in a biological sample and the elimination of undesirable cross-reactivity to other substances that may be present in the sample.
A lateral flow testing device is provided for testing a biological fluid for the presence of methamphetamines. The device includes a substrate element such as a nitrocellulose strip, including an antibody zone and an immobilized drug conjugate zone for detecting presence of methamphetamines, and an on-board chemical reactant for preventing undesirable cross-reactivity to ephedrine and/or pseudoephedrine that may be present in the biological fluid being tested. Preferably, the on-board chemical reactant is sodium periodate. Methods for preparing test devices are provided including the step of striping a substrate sheet with a solution containing sodium periodate during manufacture of methamphetamine lateral flow test strips.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2002</creationdate><recordtype>patent</recordtype><sourceid>EFH</sourceid><recordid>eNrjZLD2SSxJLUrMUUjLyS9XKEktLsnMS1dISS3LTE5VKM8syVDIz9NNyk8sSlFIzkjNzUwGKi1KTUwuScwr4WFgTUvMKU7lhdLcDApuriHOHrqlxQVAU_NKiuPTixJBlIGZiaWRoZG5MRFKAGvYMC8</recordid><startdate>20021210</startdate><enddate>20021210</enddate><creator>Goodell, Raegan E</creator><creator>Blevins, Dennis D</creator><scope>EFH</scope></search><sort><creationdate>20021210</creationdate><title>Lateral flow testing device with on-board chemical reactant</title><author>Goodell, Raegan E ; Blevins, Dennis D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_grants_064921273</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2002</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Goodell, Raegan E</creatorcontrib><creatorcontrib>Blevins, Dennis D</creatorcontrib><creatorcontrib>Varian, Inc</creatorcontrib><collection>USPTO Issued Patents</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Goodell, Raegan E</au><au>Blevins, Dennis D</au><aucorp>Varian, Inc</aucorp><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Lateral flow testing device with on-board chemical reactant</title><date>2002-12-10</date><risdate>2002</risdate><abstract>The present invention generally relates to a test device and method for testing a biological fluid for the presence of certain "drugs of abuse", and more specifically relates to a lateral flow testing device and method for testing for the presence of methamphetamines in a biological sample and the elimination of undesirable cross-reactivity to other substances that may be present in the sample.
A lateral flow testing device is provided for testing a biological fluid for the presence of methamphetamines. The device includes a substrate element such as a nitrocellulose strip, including an antibody zone and an immobilized drug conjugate zone for detecting presence of methamphetamines, and an on-board chemical reactant for preventing undesirable cross-reactivity to ephedrine and/or pseudoephedrine that may be present in the biological fluid being tested. Preferably, the on-board chemical reactant is sodium periodate. Methods for preparing test devices are provided including the step of striping a substrate sheet with a solution containing sodium periodate during manufacture of methamphetamine lateral flow test strips.</abstract><oa>free_for_read</oa></addata></record> |
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| title | Lateral flow testing device with on-board chemical reactant |
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