Kappa agonist compounds, pharmaceutical formulations and method of prevention and treatment of pruritus therewith

Kappa agonist compounds, pharmaceutical formulations and method of prevention and treatment of pruritus therewith

1. Field of the Invention Method for the prevention or treatment of pruritus with anti-pruritic compounds is provided.The compounds of formulae I, II, IIA, III, IIIA, IV and IVA have the structure: whereinR, R, R, R; andX, X, X, X, X;Y, Z and n are as described in the specification.

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Wei Yuan, Maycock, Alan L, Marella, Anthony Michael, Kumar, Virendra, Gaul, Forrest, Guo, Deqi
Format: Patent
Sprache:eng
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Zusammenfassung:1. Field of the Invention Method for the prevention or treatment of pruritus with anti-pruritic compounds is provided.The compounds of formulae I, II, IIA, III, IIIA, IV and IVA have the structure: whereinR, R, R, R; andX, X, X, X, X;Y, Z and n are as described in the specification.