Imidazole derivatives having an inhibitory activity for farnesyl transferase and process for preparation thereof
The present invention relates to a novel imidazole derivative represented by the following formula (1) which shows an inhibitory activity against farnesyl transferase: The present invention relates to a novel imidazole derivative represented by formula (1) which shows an inhibitory activity against...
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| creator | Lee, Hyun Il Koh, Jong Sung Lee, Jin Ho Jung, Won Hee Shin, You Seung Chung, Hyun Ho Kim, Jong Hyun Ro, Seong Gu Choi, Tae Saeng Jeong, Shin Wu Kwak, Tae Hwan Ahn, In Ae Kim, Hyun Sung Lee, Sun Hwa Kim, Kwi Hwa Yoo, Jung Kwon |
| description | The present invention relates to a novel imidazole derivative represented by the following formula (1) which shows an inhibitory activity against farnesyl transferase:
The present invention relates to a novel imidazole derivative represented by formula (1) which shows an inhibitory activity against farnesyl transferase or pharmaceutically acceptable salts or isomers thereof, in which A, nand Y are defined in the specification; to a process for preparation of the compound of formula (1); to intermediates which are used in the preparation of the compound of formula (1): and to a pharmaceutical composition comprising the compound of formula (1) as an active ingredient. |
| format | Patent |
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The present invention relates to a novel imidazole derivative represented by formula (1) which shows an inhibitory activity against farnesyl transferase or pharmaceutically acceptable salts or isomers thereof, in which A, nand Y are defined in the specification; to a process for preparation of the compound of formula (1); to intermediates which are used in the preparation of the compound of formula (1): and to a pharmaceutical composition comprising the compound of formula (1) as an active ingredient.</description><language>eng</language><creationdate>2002</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6472526$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,780,802,885,64039</link.rule.ids><linktorsrc>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6472526$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Lee, Hyun Il</creatorcontrib><creatorcontrib>Koh, Jong Sung</creatorcontrib><creatorcontrib>Lee, Jin Ho</creatorcontrib><creatorcontrib>Jung, Won Hee</creatorcontrib><creatorcontrib>Shin, You Seung</creatorcontrib><creatorcontrib>Chung, Hyun Ho</creatorcontrib><creatorcontrib>Kim, Jong Hyun</creatorcontrib><creatorcontrib>Ro, Seong Gu</creatorcontrib><creatorcontrib>Choi, Tae Saeng</creatorcontrib><creatorcontrib>Jeong, Shin Wu</creatorcontrib><creatorcontrib>Kwak, Tae Hwan</creatorcontrib><creatorcontrib>Ahn, In Ae</creatorcontrib><creatorcontrib>Kim, Hyun Sung</creatorcontrib><creatorcontrib>Lee, Sun Hwa</creatorcontrib><creatorcontrib>Kim, Kwi Hwa</creatorcontrib><creatorcontrib>Yoo, Jung Kwon</creatorcontrib><creatorcontrib>LG Chemical Ltd</creatorcontrib><title>Imidazole derivatives having an inhibitory activity for farnesyl transferase and process for preparation thereof</title><description>The present invention relates to a novel imidazole derivative represented by the following formula (1) which shows an inhibitory activity against farnesyl transferase:
The present invention relates to a novel imidazole derivative represented by formula (1) which shows an inhibitory activity against farnesyl transferase or pharmaceutically acceptable salts or isomers thereof, in which A, nand Y are defined in the specification; to a process for preparation of the compound of formula (1); to intermediates which are used in the preparation of the compound of formula (1): and to a pharmaceutical composition comprising the compound of formula (1) as an active ingredient.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2002</creationdate><recordtype>patent</recordtype><sourceid>EFH</sourceid><recordid>eNqNjEEKwkAMAHvxIOof8gFBqtYHiKJ37xLbbBuo2SWJhfX1LuIDPM1hhplX6frkDt9xJOhIeULniQwGnFh6QAGWgR_sUTNgWyR7hhAVAqqQ5RFcUSyQolHpO0gaWzL7RkkpoZZnFPCBlGJYVrOAo9Hqx0UF59PteFm_LKGTuN37cizYNLtDva-b7R_JB6aWRXc</recordid><startdate>20021029</startdate><enddate>20021029</enddate><creator>Lee, Hyun Il</creator><creator>Koh, Jong Sung</creator><creator>Lee, Jin Ho</creator><creator>Jung, Won Hee</creator><creator>Shin, You Seung</creator><creator>Chung, Hyun Ho</creator><creator>Kim, Jong Hyun</creator><creator>Ro, Seong Gu</creator><creator>Choi, Tae Saeng</creator><creator>Jeong, Shin Wu</creator><creator>Kwak, Tae Hwan</creator><creator>Ahn, In Ae</creator><creator>Kim, Hyun Sung</creator><creator>Lee, Sun Hwa</creator><creator>Kim, Kwi Hwa</creator><creator>Yoo, Jung Kwon</creator><scope>EFH</scope></search><sort><creationdate>20021029</creationdate><title>Imidazole derivatives having an inhibitory activity for farnesyl transferase and process for preparation thereof</title><author>Lee, Hyun Il ; Koh, Jong Sung ; Lee, Jin Ho ; Jung, Won Hee ; Shin, You Seung ; Chung, Hyun Ho ; Kim, Jong Hyun ; Ro, Seong Gu ; Choi, Tae Saeng ; Jeong, Shin Wu ; Kwak, Tae Hwan ; Ahn, In Ae ; Kim, Hyun Sung ; Lee, Sun Hwa ; Kim, Kwi Hwa ; Yoo, Jung Kwon</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_grants_064725263</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2002</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Lee, Hyun Il</creatorcontrib><creatorcontrib>Koh, Jong Sung</creatorcontrib><creatorcontrib>Lee, Jin Ho</creatorcontrib><creatorcontrib>Jung, Won Hee</creatorcontrib><creatorcontrib>Shin, You Seung</creatorcontrib><creatorcontrib>Chung, Hyun Ho</creatorcontrib><creatorcontrib>Kim, Jong Hyun</creatorcontrib><creatorcontrib>Ro, Seong Gu</creatorcontrib><creatorcontrib>Choi, Tae Saeng</creatorcontrib><creatorcontrib>Jeong, Shin Wu</creatorcontrib><creatorcontrib>Kwak, Tae Hwan</creatorcontrib><creatorcontrib>Ahn, In Ae</creatorcontrib><creatorcontrib>Kim, Hyun Sung</creatorcontrib><creatorcontrib>Lee, Sun Hwa</creatorcontrib><creatorcontrib>Kim, Kwi Hwa</creatorcontrib><creatorcontrib>Yoo, Jung Kwon</creatorcontrib><creatorcontrib>LG Chemical Ltd</creatorcontrib><collection>USPTO Issued Patents</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Lee, Hyun Il</au><au>Koh, Jong Sung</au><au>Lee, Jin Ho</au><au>Jung, Won Hee</au><au>Shin, You Seung</au><au>Chung, Hyun Ho</au><au>Kim, Jong Hyun</au><au>Ro, Seong Gu</au><au>Choi, Tae Saeng</au><au>Jeong, Shin Wu</au><au>Kwak, Tae Hwan</au><au>Ahn, In Ae</au><au>Kim, Hyun Sung</au><au>Lee, Sun Hwa</au><au>Kim, Kwi Hwa</au><au>Yoo, Jung Kwon</au><aucorp>LG Chemical Ltd</aucorp><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Imidazole derivatives having an inhibitory activity for farnesyl transferase and process for preparation thereof</title><date>2002-10-29</date><risdate>2002</risdate><abstract>The present invention relates to a novel imidazole derivative represented by the following formula (1) which shows an inhibitory activity against farnesyl transferase:
The present invention relates to a novel imidazole derivative represented by formula (1) which shows an inhibitory activity against farnesyl transferase or pharmaceutically acceptable salts or isomers thereof, in which A, nand Y are defined in the specification; to a process for preparation of the compound of formula (1); to intermediates which are used in the preparation of the compound of formula (1): and to a pharmaceutical composition comprising the compound of formula (1) as an active ingredient.</abstract><oa>free_for_read</oa></addata></record> |
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| title | Imidazole derivatives having an inhibitory activity for farnesyl transferase and process for preparation thereof |
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