Glycoprotein IIB/IIIA antagonists

Glycoprotein IIB/IIIA antagonists

This invention relates to bicyclic compounds useful as glycoprotein IIb/IIIa antagonists for the prevention of thrombosis. This invention relates to certain bicyclic compounds having a nucleus formed of two fused six membered rings, for example, isoquinoline, isoquinolone, tetrahydronaphthalene, dih...

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Hauptverfasser: Fisher, Matthew J, Happ, Anne Marie, Jakubowski, Joseph A, Kinnick, Michael Dean, Kline, Allen D, Morin, Jr., John Michael, Sall, Daniel J, Skelton, Marshall A, Vasileff, Robert Theodore
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Sprache:eng
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creator Fisher, Matthew J
Happ, Anne Marie
Jakubowski, Joseph A
Kinnick, Michael Dean
Kline, Allen D
Morin, Jr., John Michael
Sall, Daniel J
Skelton, Marshall A
Vasileff, Robert Theodore
description This invention relates to bicyclic compounds useful as glycoprotein IIb/IIIa antagonists for the prevention of thrombosis. This invention relates to certain bicyclic compounds having a nucleus formed of two fused six membered rings, for example, isoquinoline, isoquinolone, tetrahydronaphthalene, dihydronaphthalene, or tetralone, substituted with both basic and acidic functionality, which are useful in inhibition of platelet aggregation.
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This invention relates to certain bicyclic compounds having a nucleus formed of two fused six membered rings, for example, isoquinoline, isoquinolone, tetrahydronaphthalene, dihydronaphthalene, or tetralone, substituted with both basic and acidic functionality, which are useful in inhibition of platelet aggregation.</abstract><oa>free_for_read</oa></addata></record>
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title Glycoprotein IIB/IIIA antagonists
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