Glycoprotein IIB/IIIA antagonists

This invention relates to bicyclic compounds useful as glycoprotein IIb/IIIa antagonists for the prevention of thrombosis. This invention relates to certain bicyclic compounds having a nucleus formed of two fused six membered rings, for example, isoquinoline, isoquinolone, tetrahydronaphthalene, dih...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	Fisher, Matthew J, Happ, Anne Marie, Jakubowski, Joseph A, Kinnick, Michael Dean, Kline, Allen D, Morin, Jr., John Michael, Sall, Daniel J, Skelton, Marshall A, Vasileff, Robert Theodore
Format:	Patent
Sprache:	eng
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	This invention relates to bicyclic compounds useful as glycoprotein IIb/IIIa antagonists for the prevention of thrombosis. This invention relates to certain bicyclic compounds having a nucleus formed of two fused six membered rings, for example, isoquinoline, isoquinolone, tetrahydronaphthalene, dihydronaphthalene, or tetralone, substituted with both basic and acidic functionality, which are useful in inhibition of platelet aggregation.