Farnesyl transferase inhibitors having a piperidine structure and process for preparation thereof
The present invention relates to a novel piperidine derivative represented by the following formula (1) which shows an inhibitory activity against farnesyl transferase: The present invention relates to a novel piperidine derivative represented by formula (1) which shows an inhibitory activity agains...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | Shin, You Seung Koh, Jong Sung Lee, Hyun Il Lee, Jin Ho Kim, Jong Hyun Chung, Hyun Ho Kim, Kwi Hwa Kwak, Tae Hwan Ro, Seong Gu Ahn, In Ae Choi, Tae Saeng Oh, Young Hoon Kim, Chung Mi Lee, Sun Hwa Kim, Hyun Sung |
| description | The present invention relates to a novel piperidine derivative represented by the following formula (1) which shows an inhibitory activity against farnesyl transferase:
The present invention relates to a novel piperidine derivative represented by formula (1) which shows an inhibitory activity against farnesyl transferase or pharmaceutically acceptable salts thereof, in which A, E and G are defined in the specification; to a process for preparation of the compound of formula (1); to an intermediate which is used in the preparation of the compound of formula (1); and to a pharmaceutical composition comprising the compound of formula (1) as an active ingredient. |
| format | Patent |
| fullrecord | <record><control><sourceid>uspatents_EFH</sourceid><recordid>TN_cdi_uspatents_grants_06436960</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>06436960</sourcerecordid><originalsourceid>FETCH-uspatents_grants_064369603</originalsourceid><addsrcrecordid>eNqNjUEKwkAMAHvxIOof8gGhUFnwLJY-wLvENtsNlOySZAV_7x58gKeZw8DsOxxRheyzgSuKRVI0ApbEL_asBgnfLCsgFC6kvLAQmGudvSoBygJF80xmELM2p4KKzlnAEynleOx2ETej04-HDsb74zadqxV0Erfn2tYNfbgM4Rr64Y_kC1TvP7o</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Farnesyl transferase inhibitors having a piperidine structure and process for preparation thereof</title><source>USPTO Issued Patents</source><creator>Shin, You Seung ; Koh, Jong Sung ; Lee, Hyun Il ; Lee, Jin Ho ; Kim, Jong Hyun ; Chung, Hyun Ho ; Kim, Kwi Hwa ; Kwak, Tae Hwan ; Ro, Seong Gu ; Ahn, In Ae ; Choi, Tae Saeng ; Oh, Young Hoon ; Kim, Chung Mi ; Lee, Sun Hwa ; Kim, Hyun Sung</creator><creatorcontrib>Shin, You Seung ; Koh, Jong Sung ; Lee, Hyun Il ; Lee, Jin Ho ; Kim, Jong Hyun ; Chung, Hyun Ho ; Kim, Kwi Hwa ; Kwak, Tae Hwan ; Ro, Seong Gu ; Ahn, In Ae ; Choi, Tae Saeng ; Oh, Young Hoon ; Kim, Chung Mi ; Lee, Sun Hwa ; Kim, Hyun Sung ; LG Chemical Ltd</creatorcontrib><description>The present invention relates to a novel piperidine derivative represented by the following formula (1) which shows an inhibitory activity against farnesyl transferase:
The present invention relates to a novel piperidine derivative represented by formula (1) which shows an inhibitory activity against farnesyl transferase or pharmaceutically acceptable salts thereof, in which A, E and G are defined in the specification; to a process for preparation of the compound of formula (1); to an intermediate which is used in the preparation of the compound of formula (1); and to a pharmaceutical composition comprising the compound of formula (1) as an active ingredient.</description><language>eng</language><creationdate>2002</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6436960$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,780,802,885,64039</link.rule.ids><linktorsrc>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6436960$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Shin, You Seung</creatorcontrib><creatorcontrib>Koh, Jong Sung</creatorcontrib><creatorcontrib>Lee, Hyun Il</creatorcontrib><creatorcontrib>Lee, Jin Ho</creatorcontrib><creatorcontrib>Kim, Jong Hyun</creatorcontrib><creatorcontrib>Chung, Hyun Ho</creatorcontrib><creatorcontrib>Kim, Kwi Hwa</creatorcontrib><creatorcontrib>Kwak, Tae Hwan</creatorcontrib><creatorcontrib>Ro, Seong Gu</creatorcontrib><creatorcontrib>Ahn, In Ae</creatorcontrib><creatorcontrib>Choi, Tae Saeng</creatorcontrib><creatorcontrib>Oh, Young Hoon</creatorcontrib><creatorcontrib>Kim, Chung Mi</creatorcontrib><creatorcontrib>Lee, Sun Hwa</creatorcontrib><creatorcontrib>Kim, Hyun Sung</creatorcontrib><creatorcontrib>LG Chemical Ltd</creatorcontrib><title>Farnesyl transferase inhibitors having a piperidine structure and process for preparation thereof</title><description>The present invention relates to a novel piperidine derivative represented by the following formula (1) which shows an inhibitory activity against farnesyl transferase:
The present invention relates to a novel piperidine derivative represented by formula (1) which shows an inhibitory activity against farnesyl transferase or pharmaceutically acceptable salts thereof, in which A, E and G are defined in the specification; to a process for preparation of the compound of formula (1); to an intermediate which is used in the preparation of the compound of formula (1); and to a pharmaceutical composition comprising the compound of formula (1) as an active ingredient.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2002</creationdate><recordtype>patent</recordtype><sourceid>EFH</sourceid><recordid>eNqNjUEKwkAMAHvxIOof8gGhUFnwLJY-wLvENtsNlOySZAV_7x58gKeZw8DsOxxRheyzgSuKRVI0ApbEL_asBgnfLCsgFC6kvLAQmGudvSoBygJF80xmELM2p4KKzlnAEynleOx2ETej04-HDsb74zadqxV0Erfn2tYNfbgM4Rr64Y_kC1TvP7o</recordid><startdate>20020820</startdate><enddate>20020820</enddate><creator>Shin, You Seung</creator><creator>Koh, Jong Sung</creator><creator>Lee, Hyun Il</creator><creator>Lee, Jin Ho</creator><creator>Kim, Jong Hyun</creator><creator>Chung, Hyun Ho</creator><creator>Kim, Kwi Hwa</creator><creator>Kwak, Tae Hwan</creator><creator>Ro, Seong Gu</creator><creator>Ahn, In Ae</creator><creator>Choi, Tae Saeng</creator><creator>Oh, Young Hoon</creator><creator>Kim, Chung Mi</creator><creator>Lee, Sun Hwa</creator><creator>Kim, Hyun Sung</creator><scope>EFH</scope></search><sort><creationdate>20020820</creationdate><title>Farnesyl transferase inhibitors having a piperidine structure and process for preparation thereof</title><author>Shin, You Seung ; Koh, Jong Sung ; Lee, Hyun Il ; Lee, Jin Ho ; Kim, Jong Hyun ; Chung, Hyun Ho ; Kim, Kwi Hwa ; Kwak, Tae Hwan ; Ro, Seong Gu ; Ahn, In Ae ; Choi, Tae Saeng ; Oh, Young Hoon ; Kim, Chung Mi ; Lee, Sun Hwa ; Kim, Hyun Sung</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_grants_064369603</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2002</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Shin, You Seung</creatorcontrib><creatorcontrib>Koh, Jong Sung</creatorcontrib><creatorcontrib>Lee, Hyun Il</creatorcontrib><creatorcontrib>Lee, Jin Ho</creatorcontrib><creatorcontrib>Kim, Jong Hyun</creatorcontrib><creatorcontrib>Chung, Hyun Ho</creatorcontrib><creatorcontrib>Kim, Kwi Hwa</creatorcontrib><creatorcontrib>Kwak, Tae Hwan</creatorcontrib><creatorcontrib>Ro, Seong Gu</creatorcontrib><creatorcontrib>Ahn, In Ae</creatorcontrib><creatorcontrib>Choi, Tae Saeng</creatorcontrib><creatorcontrib>Oh, Young Hoon</creatorcontrib><creatorcontrib>Kim, Chung Mi</creatorcontrib><creatorcontrib>Lee, Sun Hwa</creatorcontrib><creatorcontrib>Kim, Hyun Sung</creatorcontrib><creatorcontrib>LG Chemical Ltd</creatorcontrib><collection>USPTO Issued Patents</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Shin, You Seung</au><au>Koh, Jong Sung</au><au>Lee, Hyun Il</au><au>Lee, Jin Ho</au><au>Kim, Jong Hyun</au><au>Chung, Hyun Ho</au><au>Kim, Kwi Hwa</au><au>Kwak, Tae Hwan</au><au>Ro, Seong Gu</au><au>Ahn, In Ae</au><au>Choi, Tae Saeng</au><au>Oh, Young Hoon</au><au>Kim, Chung Mi</au><au>Lee, Sun Hwa</au><au>Kim, Hyun Sung</au><aucorp>LG Chemical Ltd</aucorp><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Farnesyl transferase inhibitors having a piperidine structure and process for preparation thereof</title><date>2002-08-20</date><risdate>2002</risdate><abstract>The present invention relates to a novel piperidine derivative represented by the following formula (1) which shows an inhibitory activity against farnesyl transferase:
The present invention relates to a novel piperidine derivative represented by formula (1) which shows an inhibitory activity against farnesyl transferase or pharmaceutically acceptable salts thereof, in which A, E and G are defined in the specification; to a process for preparation of the compound of formula (1); to an intermediate which is used in the preparation of the compound of formula (1); and to a pharmaceutical composition comprising the compound of formula (1) as an active ingredient.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_uspatents_grants_06436960 |
| source | USPTO Issued Patents |
| title | Farnesyl transferase inhibitors having a piperidine structure and process for preparation thereof |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-03T05%3A44%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-uspatents_EFH&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Shin,%20You%20Seung&rft.aucorp=LG%20Chemical%20Ltd&rft.date=2002-08-20&rft_id=info:doi/&rft_dat=%3Cuspatents_EFH%3E06436960%3C/uspatents_EFH%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |