Antibodies against E-selectin
This invention relates to antibodies having specificity for E-selectin characterised in that said antibodies are whole antibodies of neutral isotype, to processes for preparing said antibodies, to pharmaceutical compositions containing said antibodies, and to medical uses of said antibodies. This in...
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| creator | Owens, Raymond John Robinson, Martyn Kim |
| description | This invention relates to antibodies having specificity for E-selectin characterised in that said antibodies are whole antibodies of neutral isotype, to processes for preparing said antibodies, to pharmaceutical compositions containing said antibodies, and to medical uses of said antibodies.
This invention relates to whole antibodies of neutral isotype having specificity for E-selection, process for their preparation (using vectors), pharmaceutical compositions containing them, and their use in therapy (e.g. for inflammatory disorders) and diagnosis. Said antibodies are variants of natural antibodies altered in the Fregion, especially in the CHdomain, so that the interactions with antibodies Freceptors and complement are absent or very low. |
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This invention relates to whole antibodies of neutral isotype having specificity for E-selection, process for their preparation (using vectors), pharmaceutical compositions containing them, and their use in therapy (e.g. for inflammatory disorders) and diagnosis. Said antibodies are variants of natural antibodies altered in the Fregion, especially in the CHdomain, so that the interactions with antibodies Freceptors and complement are absent or very low.</description><language>eng</language><creationdate>2002</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6407214$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,780,802,885,64039</link.rule.ids><linktorsrc>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6407214$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Owens, Raymond John</creatorcontrib><creatorcontrib>Robinson, Martyn Kim</creatorcontrib><creatorcontrib>Celltech Therapeutics Limited</creatorcontrib><title>Antibodies against E-selectin</title><description>This invention relates to antibodies having specificity for E-selectin characterised in that said antibodies are whole antibodies of neutral isotype, to processes for preparing said antibodies, to pharmaceutical compositions containing said antibodies, and to medical uses of said antibodies.
This invention relates to whole antibodies of neutral isotype having specificity for E-selection, process for their preparation (using vectors), pharmaceutical compositions containing them, and their use in therapy (e.g. for inflammatory disorders) and diagnosis. Said antibodies are variants of natural antibodies altered in the Fregion, especially in the CHdomain, so that the interactions with antibodies Freceptors and complement are absent or very low.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2002</creationdate><recordtype>patent</recordtype><sourceid>EFH</sourceid><recordid>eNrjZJB1zCvJTMpPyUwtVkhMT8zMKy5RcNUtTs1JTS7JzONhYE1LzClO5YXS3AwKbq4hzh66pcUFiSWpeSXF8elFiSDKwMzEwNzI0MSYCCUAoVEk1A</recordid><startdate>20020618</startdate><enddate>20020618</enddate><creator>Owens, Raymond John</creator><creator>Robinson, Martyn Kim</creator><scope>EFH</scope></search><sort><creationdate>20020618</creationdate><title>Antibodies against E-selectin</title><author>Owens, Raymond John ; Robinson, Martyn Kim</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_grants_064072143</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2002</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Owens, Raymond John</creatorcontrib><creatorcontrib>Robinson, Martyn Kim</creatorcontrib><creatorcontrib>Celltech Therapeutics Limited</creatorcontrib><collection>USPTO Issued Patents</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Owens, Raymond John</au><au>Robinson, Martyn Kim</au><aucorp>Celltech Therapeutics Limited</aucorp><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Antibodies against E-selectin</title><date>2002-06-18</date><risdate>2002</risdate><abstract>This invention relates to antibodies having specificity for E-selectin characterised in that said antibodies are whole antibodies of neutral isotype, to processes for preparing said antibodies, to pharmaceutical compositions containing said antibodies, and to medical uses of said antibodies.
This invention relates to whole antibodies of neutral isotype having specificity for E-selection, process for their preparation (using vectors), pharmaceutical compositions containing them, and their use in therapy (e.g. for inflammatory disorders) and diagnosis. Said antibodies are variants of natural antibodies altered in the Fregion, especially in the CHdomain, so that the interactions with antibodies Freceptors and complement are absent or very low.</abstract><oa>free_for_read</oa></addata></record> |
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| title | Antibodies against E-selectin |
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