Synthesis of epothilones, intermediates thereto, analogues and uses thereof

The present invention is in the field of epothilone macrolides. In particular, the present invention relates to processes for the preparation of epothilones A and B, desoxyepothilones A and B, and analogues thereof which are useful as highly specific, non-toxic anticancer therapeutics. In addition,...

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Bibliographische Detailangaben
Hauptverfasser: Danishefsky, Samuel J, Bertinato, Peter, Su, Dai-Shi, Meng, Dang Fang, Chou, Ting-Chao, Kamenecka, Ted, Sorensen, Erik J, Balog, Aaron, Savin, Kenneth A
Format: Patent
Sprache:eng
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