Methods for the synthesis of dioxoalkanoic acid compounds

The present invention is directed to methods for the synthesis of dioxoalkanoic acid compounds and derivatives useful as intermediates for diarylpyrrole therapeutic agents. More particularly, the present invention is directed to the treatment of benzoylcyclohexanone compounds with an alcohol to prov...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Ferro, Michael P, McCoy, Kathleen A
Format: Patent
Sprache:eng
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Ferro, Michael P
McCoy, Kathleen A
description The present invention is directed to methods for the synthesis of dioxoalkanoic acid compounds and derivatives useful as intermediates for diarylpyrrole therapeutic agents. More particularly, the present invention is directed to the treatment of benzoylcyclohexanone compounds with an alcohol to provide improved yields of purified 7-aryl-4,7-dioxoheptanoic acid derivatives. The invention relates to improved methods of producing aryl dioxoalkanoic acid compounds and derivatives useful as intermediates for diarylpyrrole therapeutic agents by the alcoholysis of benzoylcyclohexanone ketal compounds.
format Patent
fullrecord <record><control><sourceid>uspatents_EFH</sourceid><recordid>TN_cdi_uspatents_grants_06355812</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>06355812</sourcerecordid><originalsourceid>FETCH-uspatents_grants_063558123</originalsourceid><addsrcrecordid>eNrjZLD0TS3JyE8pVkjLL1IoyUhVKK7MA1LFmcUK-WkKKZn5FfmJOdmJefmZyQqJyZkpCsn5uQX5pXkpxTwMrGmJOcWpvFCam0HBzTXE2UO3tLggsSQ1r6Q4Pr0oEUQZmBmbmloYGhkToQQAJ_Yv0w</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Methods for the synthesis of dioxoalkanoic acid compounds</title><source>USPTO Issued Patents</source><creator>Ferro, Michael P ; McCoy, Kathleen A</creator><creatorcontrib>Ferro, Michael P ; McCoy, Kathleen A ; Orth-McNeil Pharmaceutical, Inc</creatorcontrib><description>The present invention is directed to methods for the synthesis of dioxoalkanoic acid compounds and derivatives useful as intermediates for diarylpyrrole therapeutic agents. More particularly, the present invention is directed to the treatment of benzoylcyclohexanone compounds with an alcohol to provide improved yields of purified 7-aryl-4,7-dioxoheptanoic acid derivatives. The invention relates to improved methods of producing aryl dioxoalkanoic acid compounds and derivatives useful as intermediates for diarylpyrrole therapeutic agents by the alcoholysis of benzoylcyclohexanone ketal compounds.</description><language>eng</language><creationdate>2002</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6355812$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,776,798,881,64012</link.rule.ids><linktorsrc>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6355812$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Ferro, Michael P</creatorcontrib><creatorcontrib>McCoy, Kathleen A</creatorcontrib><creatorcontrib>Orth-McNeil Pharmaceutical, Inc</creatorcontrib><title>Methods for the synthesis of dioxoalkanoic acid compounds</title><description>The present invention is directed to methods for the synthesis of dioxoalkanoic acid compounds and derivatives useful as intermediates for diarylpyrrole therapeutic agents. More particularly, the present invention is directed to the treatment of benzoylcyclohexanone compounds with an alcohol to provide improved yields of purified 7-aryl-4,7-dioxoheptanoic acid derivatives. The invention relates to improved methods of producing aryl dioxoalkanoic acid compounds and derivatives useful as intermediates for diarylpyrrole therapeutic agents by the alcoholysis of benzoylcyclohexanone ketal compounds.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2002</creationdate><recordtype>patent</recordtype><sourceid>EFH</sourceid><recordid>eNrjZLD0TS3JyE8pVkjLL1IoyUhVKK7MA1LFmcUK-WkKKZn5FfmJOdmJefmZyQqJyZkpCsn5uQX5pXkpxTwMrGmJOcWpvFCam0HBzTXE2UO3tLggsSQ1r6Q4Pr0oEUQZmBmbmloYGhkToQQAJ_Yv0w</recordid><startdate>20020312</startdate><enddate>20020312</enddate><creator>Ferro, Michael P</creator><creator>McCoy, Kathleen A</creator><scope>EFH</scope></search><sort><creationdate>20020312</creationdate><title>Methods for the synthesis of dioxoalkanoic acid compounds</title><author>Ferro, Michael P ; McCoy, Kathleen A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_grants_063558123</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2002</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Ferro, Michael P</creatorcontrib><creatorcontrib>McCoy, Kathleen A</creatorcontrib><creatorcontrib>Orth-McNeil Pharmaceutical, Inc</creatorcontrib><collection>USPTO Issued Patents</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Ferro, Michael P</au><au>McCoy, Kathleen A</au><aucorp>Orth-McNeil Pharmaceutical, Inc</aucorp><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Methods for the synthesis of dioxoalkanoic acid compounds</title><date>2002-03-12</date><risdate>2002</risdate><abstract>The present invention is directed to methods for the synthesis of dioxoalkanoic acid compounds and derivatives useful as intermediates for diarylpyrrole therapeutic agents. More particularly, the present invention is directed to the treatment of benzoylcyclohexanone compounds with an alcohol to provide improved yields of purified 7-aryl-4,7-dioxoheptanoic acid derivatives. The invention relates to improved methods of producing aryl dioxoalkanoic acid compounds and derivatives useful as intermediates for diarylpyrrole therapeutic agents by the alcoholysis of benzoylcyclohexanone ketal compounds.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_uspatents_grants_06355812
source USPTO Issued Patents
title Methods for the synthesis of dioxoalkanoic acid compounds
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-19T23%3A48%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-uspatents_EFH&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Ferro,%20Michael%20P&rft.aucorp=Orth-McNeil%20Pharmaceutical,%20Inc&rft.date=2002-03-12&rft_id=info:doi/&rft_dat=%3Cuspatents_EFH%3E06355812%3C/uspatents_EFH%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true