4-(4-hydroxystyryl) pyridine-containing substrates for an analyte dependent enzyme activation system

This invention relates to 4-(4-hydroxystyryl) pyridine-containing compounds and the use of 4-(4-hydroxystyryl) pyridine-containing compounds as peroxidase enzyme substrates in a variety of applications such as catalyzed reporter deposition. 4-(4-hydroxystyryl) pyridine-containing compounds are discl...

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Hauptverfasser:	Bobrow, Mark Norman, Roth, Kevin Aaron
Format:	Patent
Sprache:	eng
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creator	Bobrow, Mark Norman Roth, Kevin Aaron
description	This invention relates to 4-(4-hydroxystyryl) pyridine-containing compounds and the use of 4-(4-hydroxystyryl) pyridine-containing compounds as peroxidase enzyme substrates in a variety of applications such as catalyzed reporter deposition. 4-(4-hydroxystyryl) pyridine-containing compounds are disclosed as substrates for use in assays. Also, a method for detecting or quantitating an analyte is provided which includes reacting an enzyme with a 4-(4-hydroxystyryl) pyridine-containing compound to form a reactive intermediate wherein the reactive intermediate deposits covalently on a surface by binding to a receptor, wherein deposited reactive intermediates either directly or indirectly through a label generate a signal which can be detected or quantitated.
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Also, a method for detecting or quantitating an analyte is provided which includes reacting an enzyme with a 4-(4-hydroxystyryl) pyridine-containing compound to form a reactive intermediate wherein the reactive intermediate deposits covalently on a surface by binding to a receptor, wherein deposited reactive intermediates either directly or indirectly through a label generate a signal which can be detected or quantitated.</description><language>eng</language><creationdate>2002</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6355443$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,780,802,885,64039</link.rule.ids><linktorsrc>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6355443$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Bobrow, Mark Norman</creatorcontrib><creatorcontrib>Roth, Kevin Aaron</creatorcontrib><title>4-(4-hydroxystyryl) pyridine-containing substrates for an analyte dependent enzyme activation system</title><description>This invention relates to 4-(4-hydroxystyryl) pyridine-containing compounds and the use of 4-(4-hydroxystyryl) pyridine-containing compounds as peroxidase enzyme substrates in a variety of applications such as catalyzed reporter deposition. 4-(4-hydroxystyryl) pyridine-containing compounds are disclosed as substrates for use in assays. Also, a method for detecting or quantitating an analyte is provided which includes reacting an enzyme with a 4-(4-hydroxystyryl) pyridine-containing compound to form a reactive intermediate wherein the reactive intermediate deposits covalently on a surface by binding to a receptor, wherein deposited reactive intermediates either directly or indirectly through a label generate a signal which can be detected or quantitated.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2002</creationdate><recordtype>patent</recordtype><sourceid>EFH</sourceid><recordid>eNqNjEEKwjAQAHvxIOof9qiHgNDUD4jiA7zL2mxroN2E7FZcX28FHyAMzGWYZRW823r3sFDSy0St2LCDbCWGyOTaxIqRI_cg0120oJJAlwogz-BgShAoEwdiBeK3jQTYanyixsQg85PGdbXocBDa_Lyq4Hy6Hi9ukjwfWeXWF_xqf6ibxvu6_iP5AMxWQGs</recordid><startdate>20020312</startdate><enddate>20020312</enddate><creator>Bobrow, Mark Norman</creator><creator>Roth, Kevin Aaron</creator><scope>EFH</scope></search><sort><creationdate>20020312</creationdate><title>4-(4-hydroxystyryl) pyridine-containing substrates for an analyte dependent enzyme activation system</title><author>Bobrow, Mark Norman ; Roth, Kevin Aaron</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_grants_063554433</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2002</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Bobrow, Mark Norman</creatorcontrib><creatorcontrib>Roth, Kevin Aaron</creatorcontrib><collection>USPTO Issued Patents</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Bobrow, Mark Norman</au><au>Roth, Kevin Aaron</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>4-(4-hydroxystyryl) pyridine-containing substrates for an analyte dependent enzyme activation system</title><date>2002-03-12</date><risdate>2002</risdate><abstract>This invention relates to 4-(4-hydroxystyryl) pyridine-containing compounds and the use of 4-(4-hydroxystyryl) pyridine-containing compounds as peroxidase enzyme substrates in a variety of applications such as catalyzed reporter deposition. 4-(4-hydroxystyryl) pyridine-containing compounds are disclosed as substrates for use in assays. Also, a method for detecting or quantitating an analyte is provided which includes reacting an enzyme with a 4-(4-hydroxystyryl) pyridine-containing compound to form a reactive intermediate wherein the reactive intermediate deposits covalently on a surface by binding to a receptor, wherein deposited reactive intermediates either directly or indirectly through a label generate a signal which can be detected or quantitated.</abstract><oa>free_for_read</oa></addata></record>
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title	4-(4-hydroxystyryl) pyridine-containing substrates for an analyte dependent enzyme activation system
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