Process to produce stabilized carnosic acid in high concentration

The present invention describes an improved process for the extraction of an important biochemical, carnosic acid. The present invention more particularly describes an improved process for the extraction of carnosic acid from rosemary leaves a method of stabilizing the acid from decomposition and a...

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Hauptverfasser: Ben-Yosef, Gil, Garbar, Arkady
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Garbar, Arkady
description The present invention describes an improved process for the extraction of an important biochemical, carnosic acid. The present invention more particularly describes an improved process for the extraction of carnosic acid from rosemary leaves a method of stabilizing the acid from decomposition and a method of preparing the acid in high concentration. Carnosic acid is characterized in its antioxidative function and is the most active ingredient in the prevention of the oxidation of fatty acids. The biochemical was found by Linde in 1962 to exist in and by Wenkert in 1965 to exist in rosmarinus offinalis. Later the carnosic acid was found to exist also in other plants of the same family like and . Carnosic acid is phenolic diterpene (C H O ) identified by Brieskorn and Domling in 1964 to be very potent antioxidant. Its antibiotic action against stephilococus and dental caries was also reported. A novel process for the production of the natural antioxidant, carnosic acid, by extracting it from rosemary leaves with an aqueous solution of a lower alkyl alcohol in the presence of a water soluble acid is described. The extraction of the carnosic acid is very selective, i.e. very few other chemicals such as pro-oxidants from the plant are extracted. Furthermore, a method for the stabilization of the extracted acid from decomposition and a method of preparing the acid in high concentration are described.
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The present invention more particularly describes an improved process for the extraction of carnosic acid from rosemary leaves a method of stabilizing the acid from decomposition and a method of preparing the acid in high concentration. Carnosic acid is characterized in its antioxidative function and is the most active ingredient in the prevention of the oxidation of fatty acids. The biochemical was found by Linde in 1962 to exist in and by Wenkert in 1965 to exist in rosmarinus offinalis. Later the carnosic acid was found to exist also in other plants of the same family like and . Carnosic acid is phenolic diterpene (C H O ) identified by Brieskorn and Domling in 1964 to be very potent antioxidant. Its antibiotic action against stephilococus and dental caries was also reported. A novel process for the production of the natural antioxidant, carnosic acid, by extracting it from rosemary leaves with an aqueous solution of a lower alkyl alcohol in the presence of a water soluble acid is described. The extraction of the carnosic acid is very selective, i.e. very few other chemicals such as pro-oxidants from the plant are extracted. 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title Process to produce stabilized carnosic acid in high concentration
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