Novel proteins and nucleic acids encoding same
The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide...
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| creator | Patturajan, Meera Zerhusen, Bryan Kekuda, Ramesh Miller, Charles Rieger, Daniel Pena, Carol Shimkets, Richard Li, Li Berghs, Constance Zhong, Mei Casman, Stacie Voss, Edward Boldog, Ferenc Padigaru, Muralidhara Smithson, Glennda Ji, Weizhen Gorman, Linda Vernet, Corine Leite, Mario Guo, Xiaojia Anderson, David Spytek, Kimberly Gerlach, Valerie Burgess, Catherine Khramtsov, Nikolai Ort, Tatiana Ellerman, Karen Rastelli, Luca Agee, Michele Chaudhuri, Amitabha Chant, John DiPippo, Vincent Edinger, Shlomit Eisen, Andrew Gangolli, Esha Giot, Loic Ooi, Chean Rothenberg, Mark Spaderna, Steven Hjalt, Tord Liu, Xiaohong Taupier, Raymond Catterton, Elina Shenoy, Suresh |
| description | The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins. |
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Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.</description><language>eng</language><creationdate>2004</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20040014053$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,780,873,885,64058</link.rule.ids><linktorsrc>$$Uhttps://patentcenter.uspto.gov/applications/10210130$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Patturajan, Meera</creatorcontrib><creatorcontrib>Zerhusen, Bryan</creatorcontrib><creatorcontrib>Kekuda, Ramesh</creatorcontrib><creatorcontrib>Miller, Charles</creatorcontrib><creatorcontrib>Rieger, Daniel</creatorcontrib><creatorcontrib>Pena, Carol</creatorcontrib><creatorcontrib>Shimkets, Richard</creatorcontrib><creatorcontrib>Li, Li</creatorcontrib><creatorcontrib>Berghs, Constance</creatorcontrib><creatorcontrib>Zhong, Mei</creatorcontrib><creatorcontrib>Casman, Stacie</creatorcontrib><creatorcontrib>Voss, Edward</creatorcontrib><creatorcontrib>Boldog, Ferenc</creatorcontrib><creatorcontrib>Padigaru, Muralidhara</creatorcontrib><creatorcontrib>Smithson, Glennda</creatorcontrib><creatorcontrib>Ji, Weizhen</creatorcontrib><creatorcontrib>Gorman, Linda</creatorcontrib><creatorcontrib>Vernet, Corine</creatorcontrib><creatorcontrib>Leite, Mario</creatorcontrib><creatorcontrib>Guo, Xiaojia</creatorcontrib><creatorcontrib>Anderson, David</creatorcontrib><creatorcontrib>Spytek, Kimberly</creatorcontrib><creatorcontrib>Gerlach, Valerie</creatorcontrib><creatorcontrib>Burgess, Catherine</creatorcontrib><creatorcontrib>Khramtsov, Nikolai</creatorcontrib><creatorcontrib>Ort, Tatiana</creatorcontrib><creatorcontrib>Ellerman, Karen</creatorcontrib><creatorcontrib>Rastelli, Luca</creatorcontrib><creatorcontrib>Agee, Michele</creatorcontrib><creatorcontrib>Chaudhuri, Amitabha</creatorcontrib><creatorcontrib>Chant, John</creatorcontrib><creatorcontrib>DiPippo, Vincent</creatorcontrib><creatorcontrib>Edinger, Shlomit</creatorcontrib><creatorcontrib>Eisen, Andrew</creatorcontrib><creatorcontrib>Gangolli, Esha</creatorcontrib><creatorcontrib>Giot, Loic</creatorcontrib><creatorcontrib>Ooi, Chean</creatorcontrib><creatorcontrib>Rothenberg, Mark</creatorcontrib><creatorcontrib>Spaderna, Steven</creatorcontrib><creatorcontrib>Hjalt, Tord</creatorcontrib><creatorcontrib>Liu, Xiaohong</creatorcontrib><creatorcontrib>Taupier, Raymond</creatorcontrib><creatorcontrib>Catterton, Elina</creatorcontrib><creatorcontrib>Shenoy, Suresh</creatorcontrib><title>Novel proteins and nucleic acids encoding same</title><description>The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. 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Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.</abstract><oa>free_for_read</oa></addata></record> |
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| title | Novel proteins and nucleic acids encoding same |
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