Field-flow fractionation method and apparatus
An improved field-flow fractionation method and apparatus for the separation of sample species 28 contained in a carrier fluid, wherein a stream of the sample species-containing carrier fluid is forced through a flow channel 14 having a depletion wall 18 , an accumulation wall 20 , side walls, a cha...
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| creator | Jiang, Yong Miller, Michael Myers, Marcus Kummerow, Andreas Tadjiki, Soheyl Hansen, Marcia Klein, Thorsten |
| description | An improved field-flow fractionation method and apparatus for the separation of sample species
28
contained in a carrier fluid, wherein
a stream of the sample species-containing carrier fluid is forced through a flow channel
14
having a depletion wall
18
, an accumulation wall
20
, side walls, a channel inlet
10
, and a channel outlet
34
, by introducing the sample species-containing carrier fluid into the flow channel
14
through the channel inlet
10
and withdrawing the sample species-containing carrier fluid through the channel outlet
34,
a field
32
is applied to the carrier fluid in the flow channel
14
to induce a driving force on the sample species
28
acting across the flow channel
14
from the depletion wall
18
towards the accumulation wall
20
and perpendicular to the orientation of the main axis of the flow channel
14,
the sample species
28
are subjected to fractionation as they flow through the flow channel
14
and emerge as sample species fractions at the channel outlet
34,
wherein
at least one additional stream of sample species-depleted carrier fluid is introduced into the flow channel
14
through at least one orifice
12
and the relative flow rates of the different streams are adjusted such that the stream of sample species-containing carrier fluid is positioned adjacent to the accumulation wall
20
and the sample species-depleted carrier fluid is positioned between the depletion wall
18
and the sample species-containing carrier fluid,
no mechanical barrier being provided inside the flow channel
14
between the orifice
12
and the channel inlet
10
for separating the stream of sample species-depleted carrier fluid introduced through the orifice
12
and the stream of sample species-containing carrier fluid introduced through the channel inlet
10. |
| format | Patent |
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28
contained in a carrier fluid, wherein
a stream of the sample species-containing carrier fluid is forced through a flow channel
14
having a depletion wall
18
, an accumulation wall
20
, side walls, a channel inlet
10
, and a channel outlet
34
, by introducing the sample species-containing carrier fluid into the flow channel
14
through the channel inlet
10
and withdrawing the sample species-containing carrier fluid through the channel outlet
34,
a field
32
is applied to the carrier fluid in the flow channel
14
to induce a driving force on the sample species
28
acting across the flow channel
14
from the depletion wall
18
towards the accumulation wall
20
and perpendicular to the orientation of the main axis of the flow channel
14,
the sample species
28
are subjected to fractionation as they flow through the flow channel
14
and emerge as sample species fractions at the channel outlet
34,
wherein
at least one additional stream of sample species-depleted carrier fluid is introduced into the flow channel
14
through at least one orifice
12
and the relative flow rates of the different streams are adjusted such that the stream of sample species-containing carrier fluid is positioned adjacent to the accumulation wall
20
and the sample species-depleted carrier fluid is positioned between the depletion wall
18
and the sample species-containing carrier fluid,
no mechanical barrier being provided inside the flow channel
14
between the orifice
12
and the channel inlet
10
for separating the stream of sample species-depleted carrier fluid introduced through the orifice
12
and the stream of sample species-containing carrier fluid introduced through the channel inlet
10.</description><language>eng</language><creationdate>2004</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20040000519$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,780,873,885,64059</link.rule.ids><linktorsrc>$$Uhttps://patentcenter.uspto.gov/applications/10184764$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Jiang, Yong</creatorcontrib><creatorcontrib>Miller, Michael</creatorcontrib><creatorcontrib>Myers, Marcus</creatorcontrib><creatorcontrib>Kummerow, Andreas</creatorcontrib><creatorcontrib>Tadjiki, Soheyl</creatorcontrib><creatorcontrib>Hansen, Marcia</creatorcontrib><creatorcontrib>Klein, Thorsten</creatorcontrib><title>Field-flow fractionation method and apparatus</title><description>An improved field-flow fractionation method and apparatus for the separation of sample species
28
contained in a carrier fluid, wherein
a stream of the sample species-containing carrier fluid is forced through a flow channel
14
having a depletion wall
18
, an accumulation wall
20
, side walls, a channel inlet
10
, and a channel outlet
34
, by introducing the sample species-containing carrier fluid into the flow channel
14
through the channel inlet
10
and withdrawing the sample species-containing carrier fluid through the channel outlet
34,
a field
32
is applied to the carrier fluid in the flow channel
14
to induce a driving force on the sample species
28
acting across the flow channel
14
from the depletion wall
18
towards the accumulation wall
20
and perpendicular to the orientation of the main axis of the flow channel
14,
the sample species
28
are subjected to fractionation as they flow through the flow channel
14
and emerge as sample species fractions at the channel outlet
34,
wherein
at least one additional stream of sample species-depleted carrier fluid is introduced into the flow channel
14
through at least one orifice
12
and the relative flow rates of the different streams are adjusted such that the stream of sample species-containing carrier fluid is positioned adjacent to the accumulation wall
20
and the sample species-depleted carrier fluid is positioned between the depletion wall
18
and the sample species-containing carrier fluid,
no mechanical barrier being provided inside the flow channel
14
between the orifice
12
and the channel inlet
10
for separating the stream of sample species-depleted carrier fluid introduced through the orifice
12
and the stream of sample species-containing carrier fluid introduced through the channel inlet
10.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2004</creationdate><recordtype>patent</recordtype><sourceid>EFI</sourceid><recordid>eNrjZNB1y0zNSdFNy8kvV0grSkwuyczPSwQRCrmpJRn5KQqJeUBcUJBYlFhSWszDwJqWmFOcyguluRk03VxDnD10S4sLEktS80qK44FqczKTwUYUxxsZGJgYAIGpoaUxKWoBF-QxTQ</recordid><startdate>20040101</startdate><enddate>20040101</enddate><creator>Jiang, Yong</creator><creator>Miller, Michael</creator><creator>Myers, Marcus</creator><creator>Kummerow, Andreas</creator><creator>Tadjiki, Soheyl</creator><creator>Hansen, Marcia</creator><creator>Klein, Thorsten</creator><scope>EFI</scope></search><sort><creationdate>20040101</creationdate><title>Field-flow fractionation method and apparatus</title><author>Jiang, Yong ; Miller, Michael ; Myers, Marcus ; Kummerow, Andreas ; Tadjiki, Soheyl ; Hansen, Marcia ; Klein, Thorsten</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_applications_200400005193</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2004</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Jiang, Yong</creatorcontrib><creatorcontrib>Miller, Michael</creatorcontrib><creatorcontrib>Myers, Marcus</creatorcontrib><creatorcontrib>Kummerow, Andreas</creatorcontrib><creatorcontrib>Tadjiki, Soheyl</creatorcontrib><creatorcontrib>Hansen, Marcia</creatorcontrib><creatorcontrib>Klein, Thorsten</creatorcontrib><collection>USPTO Published Applications</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Jiang, Yong</au><au>Miller, Michael</au><au>Myers, Marcus</au><au>Kummerow, Andreas</au><au>Tadjiki, Soheyl</au><au>Hansen, Marcia</au><au>Klein, Thorsten</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Field-flow fractionation method and apparatus</title><date>2004-01-01</date><risdate>2004</risdate><abstract>An improved field-flow fractionation method and apparatus for the separation of sample species
28
contained in a carrier fluid, wherein
a stream of the sample species-containing carrier fluid is forced through a flow channel
14
having a depletion wall
18
, an accumulation wall
20
, side walls, a channel inlet
10
, and a channel outlet
34
, by introducing the sample species-containing carrier fluid into the flow channel
14
through the channel inlet
10
and withdrawing the sample species-containing carrier fluid through the channel outlet
34,
a field
32
is applied to the carrier fluid in the flow channel
14
to induce a driving force on the sample species
28
acting across the flow channel
14
from the depletion wall
18
towards the accumulation wall
20
and perpendicular to the orientation of the main axis of the flow channel
14,
the sample species
28
are subjected to fractionation as they flow through the flow channel
14
and emerge as sample species fractions at the channel outlet
34,
wherein
at least one additional stream of sample species-depleted carrier fluid is introduced into the flow channel
14
through at least one orifice
12
and the relative flow rates of the different streams are adjusted such that the stream of sample species-containing carrier fluid is positioned adjacent to the accumulation wall
20
and the sample species-depleted carrier fluid is positioned between the depletion wall
18
and the sample species-containing carrier fluid,
no mechanical barrier being provided inside the flow channel
14
between the orifice
12
and the channel inlet
10
for separating the stream of sample species-depleted carrier fluid introduced through the orifice
12
and the stream of sample species-containing carrier fluid introduced through the channel inlet
10.</abstract><oa>free_for_read</oa></addata></record> |
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| language | eng |
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| source | USPTO Published Applications |
| title | Field-flow fractionation method and apparatus |
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