Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins

Methods of detecting and treating rapidly growing exogenous cells, such as Protista, or parasites, that preferentially accumulate a photoactivatable porphyrin in which 5-aminolevulinic acid or precursor thereof is administered to the patient, or contacted to the exogenous cells, in an amount suffici...

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Hauptverfasser: Kennedy, James, Pottier, Roy, Reid, Robert, Sac-Morales, Arnold, Tomalty, Lewis
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creator Kennedy, James
Pottier, Roy
Reid, Robert
Sac-Morales, Arnold
Tomalty, Lewis
description Methods of detecting and treating rapidly growing exogenous cells, such as Protista, or parasites, that preferentially accumulate a photoactivatable porphyrin in which 5-aminolevulinic acid or precursor thereof is administered to the patient, or contacted to the exogenous cells, in an amount sufficient to induce synthesis fluorescence and/or photosensitizing concentrations of a protoporphyrin IX in the exogenous cells, followed by exposure of the exogenous cells to light of photoactivating wavelengths.
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title Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins
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