Functional lentiviral vector from an MLV-based backbone

Disclosed are gene therapy vectors based on chimeric murine leukemia virus-feline immunodeficiency virus gene therapy vectors which are suitable for a wide variety of gene therapy applications. Also disclosed are related packaging cell lines, methods for production, and methods of use.

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Bibliographische Detailangaben
Hauptverfasser: Dubensky, Thomas, Gasmi, Mehdi, Sauter, Sybille
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Disclosed are gene therapy vectors based on chimeric murine leukemia virus-feline immunodeficiency virus gene therapy vectors which are suitable for a wide variety of gene therapy applications. Also disclosed are related packaging cell lines, methods for production, and methods of use.