Methods and products for identifying modulators of P2X7 receptor activity, and their use in the treatment of skeletal disorders

Methods and products for identifying modulators of P2X7 receptor activity, and their use in the treatment of skeletal disorders

Disclosed are methods for screening compounds to identify therapeutic candidates for modulating bone mass and/or bone mineral density, as well as methods for treating skeletal disorders characterized by decreased bone mass and/or bone mineral density. The methods are based upon the identification an...

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Hauptverfasser: Ke, HuaZhu, Gabel, Christopher
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Sprache:eng
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creator Ke, HuaZhu
Gabel, Christopher
description Disclosed are methods for screening compounds to identify therapeutic candidates for modulating bone mass and/or bone mineral density, as well as methods for treating skeletal disorders characterized by decreased bone mass and/or bone mineral density. The methods are based upon the identification and use of agonists of the P2X7 receptor.
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title Methods and products for identifying modulators of P2X7 receptor activity, and their use in the treatment of skeletal disorders
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